Technical field

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The Yamanouchi Pharmaceutical Co., Ltd., , Yamanouchi Pharma Technologies, Inc. patent solves the following problem:

As for pharmaceutical dosage form for oral use, a tablet, a capsule, a granule, a powder and the like are mentioned. However, these dosage forms have some issues if a patient takes them. For example, on a tablet or a capsule, if the patient is a man of advanced age or a child, there are some cases that they love getting the pharmaceutical preparation because it is difficult for them, to destroy them or to prepare stick in the throat or esophagus. Furthermore, part of a granule or a powder, in some cases they love getting preparations under the reason that it is difficult for them, to destroy them with his stay in buccal hole or the reason that they choke when taking the dose. From a compliance to take the pharmaceutical preparation is tumbling in the case, it intends to take the easy pharmaceutical dosage forms, and as a result of a broken preparation buccal cavity being studied and developed.

Our analysis of this patent is as follows:

Yamanouchi Pharmaceutical Co., Ltd., , Yamanouchi Pharma Technologies, Inc.’s patent US 6803054 B2 deals with Technical field.
The present invention relates to a quick disintegrating tablets in the buccal cavity, comprising: a mixture, consisting of a drug, a sugar (A), and is similar to an amorphous sugar (B) , and after building a tablet, it is humidified and dried. In particular, the present invention relates to a quick disintegrating tablets in the buccal cavity comprising: a mixture; consisting of a drug, a sugar (A), and is similar to an amorphous sugar (B) amounting to an amorphous-forming sugar crystals had dissolved to a treatment permitted solvent, the amorphous sugar extracted from the solution by removing to be, and after the formation of a board, and it is humidified and dried. The tablets of the present invention is to provide stability against moisture stored, because the amorphous sugar changed the crystalline state in a nonreversible reaction after it is humidified and dried in a manufacturing process. The tablets of the present invention is further to provide a design for the pharmaceutical preparation with respect to the strength of a drug, because the tablets produced in a form of a sugar and similar amorphous sugar. Furthermore, the tablets of the present invention is to provide a production process by using a common granulating machine and through the use of a common tablet machine.

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