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The Incyte Corporation patent solves the following problem:
The cytoskeleton, a cytoplasmic protein fiber system, mediated cell form, structure, and movement. cytoskeleton supports the cell membrane and forms tracks organelles and other elements move in the cytosol. cytoskeleton is a dynamic structure that allows the cells to adopt different forms and in obeying the action. Major cytoskeletal fibers are microfilaments, microtubules, and intermediate filaments. Motor proteins including myosin, dynein and kinesin, drive or movement along the fibers. Accessories or associated protein modification or structural strength of the fibers while cytoskeletal membrane anchors connect the fibers to the cell membrane.
Our analysis of this patent is as follows:
Incyte Corporation’s patent US 6962799 B2 deals with Microtubule-associated proteins and tubulins.
the invention provides human microtubule-associated protein and tubulins (MICAPTUB) and polynucleotides which identify and encode MICAPTUB. invention also provides expression vector, host cells, antibodies, agonists and antagonists. invention also provides methods for diagnosing, treating, or preventing diseases associated with aberrant expression of MICAPTUB.
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