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The Incyte Corporation patent solves the following problem:
Signal transduction is the general process that cells respond to extracellular signals. Signal transduction across the plasma membrane began to bind a signal molecule, for example, a hormone, neurotransmitter, or growth factors, into a cell membrane receptor. receptor, thus activated, triggers an intracellular biochemical cascade that ends with the activation of an intracellular target molecule, such as a transcription factors. This process of signal transduction regulates all kinds of cell functions, including cell growth, inequality, and gene transcription.
Our analysis of this patent is as follows:
Incyte Corporation’s patent US 7378492 B2 deals with CD40-related receptor that binds CD40L.
Various embodiments of the invention provide human receptor-associated membrane protein (REMAP) and Q polynucleotides which identify and encode REMAP. Embodiments of the invention also giving expression vector, host cells, antibodies, agonists and antagonists. Some embodiments provide methods for diagnosing, treating, or preventing diseases associated with aberrant expression of REMAP.
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