Inhibition of cholera toxins by galatooligosaccharides (GOS)

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The Friesland Brands B.V. patent solves the following problem:

The invention relates to nutritional and pharmaceutical composition comprising non-digestible galactooligosaccharides (gos) and use it in particular, it relates to the use of forced species to prevent, reduce or treat diseases caused by bacteria toxins.

Our analysis of this patent is as follows:

Friesland Brands B.V.’s patent US 8202842 B2 deals with Inhibition of cholera toxins by galatooligosaccharides (GOS).
The invention relates to nutritional and pharmaceutical composition comprising non-digestible galactooligosaccharides (gos) and use it. In particular, it relates to the use of forced species to prevent or treat diseases caused by bacteria toxins. When using gos with a polymerization degree of 5 or higher, preferably 6 or higher, for the manufacture of a nutritional or pharmaceutical composition for the treatment or prevention of an acute or chronic disease associated with or for extrusion and / or uptake of a cholera toxin family. which is also a way to provide a gos particle capable of inhibiting cholera toxin (Ctx) binding to GM1 and fragments obtainable so.

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Encapsulated tiotropium containing powder formulation for inhalation

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The Boehringer Ingelheim Pharma Gmbh & Co. Kg patent solves the following problem:

Tiotropium bromide is known from European Patent Application EP 418 716 A1 and the following chemical structure:

Our analysis of this patent is as follows:

Boehringer Ingelheim Pharma Gmbh & Co. Kg’s patent US 8197845 B2 deals with Encapsulated tiotropium containing powder formulation for inhalation.
The invention relates to powdered preparations containing tiotropium for inhalation, processes for preparing them as well as their use in preparing a pharmaceutical composition for the treatment of respiratory complaints, especially for treatment COPD (chronic obstructive pulmonary disease) and asthma.

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