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The Glaxo Group Limited patent solves the following problem:
Our analysis of this patent is as follows:
Glaxo Group Limited’s patent US 8470835 B2 deals with Pyrimidinecarboxamide derivatives as inhibitors of Syk kinase.
The present invention relates to a compound of formula (I): or a salt, preferably a pharmaceutically acceptable salt thereof; is an inhibitor of spleen tyrosine kinase (SYK) and therefore potential use in the treatment of diseases that result in inappropriate activation of mast cell, for example, allergic and inflammatory diseases, as well as the potential use of cancer therapy, especially heme malignancies.
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