Aminopyrimidines as SYK inhibitors

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The Merck Sharp & Dohme Corp., , Merck Canada Inc. patent solves the following problem:

Spleen Tyrosine Kinase (SYK) is a protein tyrosine kinase described as a key mediator of immunoreceptor signaling a host of inflammatory cells including mast cells, B-cells, macrophages and neutrophils. These immunoreceptors, including Fc receptor and the B-cell receptor, is important for allergic diseases, and antibody-mediated autoimmune diseases and thus pharmacologically interfering SYK conceivably treat these diseases.

Our analysis of this patent is as follows:

Merck Sharp & Dohme Corp., , Merck Canada Inc.’s patent US 8759366 B2 deals with Aminopyrimidines as SYK inhibitors.
The present invention provides new pyrimidine amines of formula (I), which is a strong inhibitor of spleen tyrosine kinase, and is useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD and rheumatoid arthritis.

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Mirrored remote peripheral interface

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The Z124 patent solves the following problem:

As computers become smaller and more portable, it may be desirable to have increased ability to print on different printers from a portable computer or a mobile telecommunications device. For example, with handheld computer when the size of a mobile phone, these computers and their users often around a printer the user wants to print. Unfortunately, most handheld devices that had very little in the way of a user interface for the user to interact with a remote device like a printer.

Our analysis of this patent is as follows:

Z124’s patent US 8761831 B2 deals with Mirrored remote peripheral interface.
A mobile telecommunications / computing device to print on a printer, the device has a sensor that determines the physical orientation of the device and the device to display the document in a display according to the orientation of the devices. The device sends information to a printer over the printer to print the document in the orientation of the document shown in the schemes. The display orientation and print orientation can be portrait or landscape. The same methods can be used to control other variables printer or, more generally, variables other peripheral devices.

The revolutionary TRAN&ASSOCIATES provides patent creation and management tools to help inventors protect their inventions using the patent system. Full lawyer support to complete and file the application is available.