Low-caloric high-protein nutritional composition for the stimulation of muscle protein synthesis

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The N.V. Nutricia patent solves the following problem:

Age-related volunteers loss of muscle mass and strength occurs during the ages and is called sarcopenia [1]. As the degenerative loss of skeletal muscle mass, it occurs at a rate of 3-8% per decade after the age of 30 years, and accelerate from 60 years of age. The two impaired muscle mass and muscle strength associated with age-related loss of muscle function.

Our analysis of this patent is as follows:

N.V. Nutricia’s patent US 8846759 B2 deals with Low-caloric high-protein nutritional composition for the stimulation of muscle protein synthesis.
The present invention relates to the use of a low-caloric high-protein nutritional composition for use in the prevention or treatment of a disease or condition in a mammal, including muscle decline, as well as specific low-caloric high-protein nutritional composition for stimulating muscle protein synthesis in a mammal. In particular, the invention relates to the use of a nutritional composition comprising per 100 kcal: (i) at least 12 g of proteinaceous matter comprising at least about 80 weight% of whey protein, relative to total proteinaceous matter, and containing at least 11 weight% of leucine, relative to the total proteinaceous matter, at least 20 weight% in a free form, relative to the total leucine, ( ii) a source of fat and a source of digestible carbohydrates, for the prevention or treatment of a disease or condition involving reduced muscle in a mammal, especially in an old mammal, which nutritional composition administered as 1 to 2 servings daily, each serving consisting of between 80 and 200 kcal.

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User interface with screen spanning icon morphing

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The Z124 patent solves the following problem:

While the computing and communications functions for handheld devices Computing becomes more powerful, the user interface and display elements such devices have evolved by trying to adapt user interface regime for the personal computer for use in handheld devices Computing . However, this attempt to adapt the user interface of the regime met with various obstacles.

Our analysis of this patent is as follows:

Z124’s patent US 8842080 B2 deals with User interface with screen spanning icon morphing.
Methods and apparatus for indicating a state of an application that displayable on one or more displays in a handheld device Computing. An icon will be given showing the position and / or the potential application statuses (for example, if the application is expandable and / or expanded). The image may be movable between a first position and a second position depending on the status of applications. The icon changes from the first state to the second state becomes animation with a live or change applications in the display state. Thus, a user can carry the icon to determine the status of the application with respect to one or more displays (for example, if the application is expandable, expanded, or expansion).

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Process for making particles for delivery of drug nanoparticles

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The Nanomaterials Technology Pte Ltd patent solves the following problem:

Artificial or natural drugs aim to serve as a cure or preventive agents for diseases and may be administered to the body by methods such as injection or ingestion. In comparing the different routes of drug administration is, ingestion or oral administration is preferred as it is less painful and have a higher rate of patient compliance. It is also a more convenient and simple or uncomplicated manner as compared to injection.

Our analysis of this patent is as follows:

Nanomaterials Technology Pte Ltd’s patent US 8835376 B2 deals with Process for making particles for delivery of drug nanoparticles.
A process for making the particles to deliver drug nanoparticles is revealed here. The process comprises the steps of (a) forming a suspension of drug nanoparticles by mixing a precipitant solution with an anti-solvent solution under micro-mixing environment, which formed nanoparticles with a narrow particle size distribution; (B) to provide an excipient at least one of the precipitant solution, the anti-solvent solution and the suspension of nanoparticles drug, the excipient selected to continue in the said drug nanoparticles in a scattered state when in liquid form; and (c) drying the suspension of nanoparticles drug containing the excipient therein to remove solvent, wherein the removal of the excipient may cause the strengthening and thus forming micro-sized matrix particles, each micro-sized particle containing drug nanoparticles dispersed in a solid matrix excipient.

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