Method for treating cancer using an antibody that inhibits notch4 signaling

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The The Regents Of The University Of Michigan patent solves the following problem:

Cancer remains the number two cause of death in this country, resulting in more than 500,000 deaths each year. Despite progress in detection and treatment, cancer mortality remains high. Despite remarkable progress in understanding the molecular basis of cancer, this knowledge has not yet translated into effective therapeutic strategies.

Our analysis of this patent is as follows:

The Regents Of The University Of Michigan’s patent US 9089556 B2 deals with Method for treating cancer using an antibody that inhibits notch4 signaling.
invention provides methods for treating cancer by administering to a patient having a solid tumor in a therapeutically effective amount of an antibody against Delta-like ligand 4 (Dll4) or others notch road components. The strong tumor may contain strong tumor stem cells.

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