Bipyridylaminopyridines as Syk inhibitors

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The Merck Sharp & Dohme Corp., , Merck Canada Inc. patent solves the following problem:

Spleen Tyrosine Kinase (SYK) is a protein tyrosine kinase described as a key mediator of immunoreceptor signaling a host of inflammatory cells including mast cells, B-cells, macrophages and neutrophils. These immunoreceptors, including Fc receptor and the B-cell receptor, is important for allergic diseases, and antibody-mediated autoimmune diseases and thus pharmacologically interfering SYK conceivably treat these diseases.

Our analysis of this patent is as follows:

Merck Sharp & Dohme Corp., , Merck Canada Inc.’s patent US 9145391 B2 deals with Bipyridylaminopyridines as Syk inhibitors.
The present invention provides new pyrimidine amines of formula I are potent inhibitor of spleen tyrosine kinase, or prodrugs thereof, and useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD and rheumatoid arthritis and cancer.

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Nutritional formulation for promoting catch-up growth

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The Nestec S.A. patent solves the following problem:

It has been recognized for many years that the growth pattern of young mammals who suffer stress as a result of physical illness or injury or psychological trauma is often interrupted. If the young mammal a swift recovery and adequate nutrition is, then it can compensate for the growth that occurred during the period of stress and this sudden rapid growth known arrest growth. However, this does not always happen. For example, the young mammal may suffer from anorexia both during the illness or injury and his immediate human food and may therefore be limited. In severe cases these animals never reach the physical size that it would have reached a pressure not suffered.

Our analysis of this patent is as follows:

Nestec S.A.’s patent US 9144250 B2 deals with Nutritional formulation for promoting catch-up growth.
This invention relates to a nutritional formulation comprising a N3 long-chain polyunsaturated fatty acid (LC-PUFA), a prebiotic fiber and a probiotic bacterial strain mixture act in a synergistic way promote footage growth in young mammals whose growth has to be wrong because the young mammal has been subjected to physical or mental stress.

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Drag reduction of a tractor trailer using guide vanes

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The Clarkson University patent solves the following problem:

The present invention relates to a vehicle with a gear mounted thereon for reducing aerodynamic drag and, particularly, to a guide vane device with an airfoil cross-section mounted on the aft part of a a tractor trailer.

Our analysis of this patent is as follows:

Clarkson University’s patent US 9139238 B2 deals with Drag reduction of a tractor trailer using guide vanes.
The present invention relates to a vehicle with a gear mounted thereon for reducing aerodynamic drag and, particularly, to a guide vane device with an airfoil cross-section mounted on the aft part of a a tractor trailer.

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Presentation of document history in a web browsing application

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The Domo, Inc. patent solves the following problem:

Electronic user devices able to work with an ever-growing number of types of documents and projects online. Users can access documents, hosted application providers online, from their electronic devices, often through a web browsing application. Google Docs, Microsoft Office Live, collaborative internetlintranet website like pages, and others, are examples of services that allows users to make various kinds of documents (eg word processing, spreadsheets, presentations, etc.) online and invite other people to revise these documents away. Changes to a document that the user is captured in the form of document revision. A user can access a shared online documents, to see the various states in the document, which a state (also referred to as a revision) in a document may include changes made by other users. The changes mostly delineated in different colors, fonts, formatting, little signs, etc.

Our analysis of this patent is as follows:

Domo, Inc.’s patent US 9135228 B2 deals with Presentation of document history in a web browsing application.
In a joint computing environment, a method and system for displaying revision associated with a host of electronic document states. According to the disclosed methods and systems, selected revision to an electronic document to be shown to a user, an aviation visual history play back the evolution of electronic documents. The electronic document can be displayed in a web browsing application, using a Document Object Model (DOM) to recover the selected revision with Asynchronous JavaScript and XML (Ajax) calls to a remote device / server.

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Dual display cursive touch input

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The Z124 patent solves the following problem:

A substantial number of handheld devices Computing, such as cellular phones, tablets, and E-Readers, make use of a touch screen display will not only save the display information to the user, but also to take inputs from the user's command interface. While touch screen display can increase the configurability of the handheld device and to provide a wide variety of user interface options, this flexibility often comes at a price. The two use the touch screen to provide for and receive user commands, while flexible for the user, in order to obfuscate the display, and cause visual clutter, thus leading to user frustration and loss of yield.

Our analysis of this patent is as follows:

Z124’s patent US 9128659 B2 deals with Dual display cursive touch input.
These methods and devices including providing a device having at least a first screen and a secondary screen; receiving a first input, where the first input comprising a cursive input on the first screen; processing the first input to estimate a character based on previous input; to display the estimated character (s); and to exercise a choice, where the selection includes a choice of traits selected from the estimated character (s).

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Dual display pinyin touch input

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The Z124 patent solves the following problem:

A substantial number of handheld devices Computing, such as cellular phones, tablets, and E-Readers, make use of a touch screen display will not only save the display information to the user, but also to take inputs from the user's command interface. While touch screen display can increase the configurability of the handheld device and to provide a wide variety of user interface options, this flexibility often comes at a price. The two use the touch screen to provide for and receive user commands, while flexible for the user, in order to obfuscate the display, and cause visual clutter, thus leading to user frustration and loss of yield.

Our analysis of this patent is as follows:

Z124’s patent US 9128660 B2 deals with Dual display pinyin touch input.
These methods and devices including providing a device having at least a first screen and a secondary screen; receiving a first input, where the first input comprising a Pinyin input on the first screen; processing the first input to estimate a character based on previous input; to display the estimated character (s); and to exercise a choice, where the selection includes a choice of traits selected from the estimated character (s).

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Bifidobacterium for dust mite allergy

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The N.V. Nutricia patent solves the following problem:

House dust mite (Dermatophagoides) allergy is a hypersensitive reaction to proteins in the elimination of house dust mites and can result in respiratory insufficiencies as airway obstruction and bronchial hyperreactivity. The hypersensitivity reaction is called dust mite induced respiratory lack of this document. House dust mites found in almost all households. The elimination products of dust mites can be a serious threat to the said sensitive products as well as elimination of critical ill patients. The dust mites are not visible to the unaided eye, and thus difficult to identify in the house.

Our analysis of this patent is as follows:

N.V. Nutricia’s patent US 9119414 B2 deals with Bifidobacterium for dust mite allergy.
A composition comprising Bifidobacterium breve for use in improving lung function in human subjects suffering from dust mite allergies.

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Pyridyl aminopyridines as Syk inhibitors

You’ve invested time, talent, and energy into making a dent in the universe with your invention and ideas. Now it’s time for Utility, Provisional or Design Patent Creation with PowerPatent software and services.

The Merck Sharp & Dohme Corp. patent solves the following problem:

Spleen Tyrosine Kinase (SYK) is a protein tyrosine kinase described as a key mediator of immunoreceptor signaling a host of inflammatory cells including mast cells, B-cells, macrophages and neutrophils. These immunoreceptors, including Fc receptor and the B-cell receptor, is important for allergic diseases, and antibody-mediated autoimmune diseases and thus pharmacologically interfering SYK conceivably treat these diseases.

Our analysis of this patent is as follows:

Merck Sharp & Dohme Corp.’s patent US 9120785 B2 deals with Pyridyl aminopyridines as Syk inhibitors.
The present invention provides new pyrimidine amines of formula I are potent inhibitor of spleen tyrosine kinase, and is useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD, rheumatoid arthritis, and cancer .

The revolutionary TRAN&ASSOCIATES provides patent creation and management tools to help inventors protect their inventions using the patent system. Full lawyer support to complete and file the application is available.

Non-digestible oligosaccharides for oral induction of tolerance against dietary proteins

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The N.V. Nutricia patent solves the following problem:

During the common process of nutrition in food proteins presented to the immune system through the gastro-intestinal tract without an immune response to ingested nutrients. This unresponsiveness is called oral immune tolerance or oral tolerance. The induction of oral immune tolerance is especially relevant for children, after being exposed for the first time to eat protein and adapt to it. If the children's oral immune tolerance is established, food allergies occur. The people who suffer from food allergies requires a specific food protein food to avoid.

Our analysis of this patent is as follows:

N.V. Nutricia’s patent US 9119838 B2 deals with Non-digestible oligosaccharides for oral induction of tolerance against dietary proteins.
Composition and the manner in which the child nutrition partially hydrolysed protein and non-digestible oligosaccharides for use in the induction of oral tolerance against the native of dietary protein.

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