2-Pyridyl carboxamide-containing spleen tyrosine kinase (SYK) inhibitors

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The Merck Sharp & Dohme Corp. patent solves the following problem:

Spleen Tyrosine Kinase (SYK) is a protein tyrosine kinase described as a key mediator of immunoreceptor signaling a host of inflammatory cells including mast cells, B-cells, macrophages and neutrophils. These immunoreceptors, including Fc receptor and the B-cell receptor, is important for allergic diseases, and antibody-mediated autoimmune diseases and thus pharmacologically interfering SYK conceivably treat these diseases.

Our analysis of this patent is as follows:

Merck Sharp & Dohme Corp.’s patent US 9216173 B2 deals with 2-Pyridyl carboxamide-containing spleen tyrosine kinase (SYK) inhibitors.
invention provides certain 2-pyridyl formamide-containing compounds of Formula (I) or pharmaceutically acceptable salts thereof, wherein A and B as described here. invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated spleen tyrosine kinase (SYK) kinase.

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Dynamic expansion of data visualizations

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The Domo, Inc. patent solves the following problem:

Our analysis of this patent is as follows:

Domo, Inc.’s patent US 9202297 B1 deals with Dynamic expansion of data visualizations.
A user can dynamically present and control the performance of secondary visualizations of data based on a selected element in a main data-aw. Introduction of secondary data visualizations presented as the user interact with the first look. In response to user input, the introduction can be dynamically expanded, allowing a user to dynamically drill down to select the elements in the first data-aw. Any input mechanisms should be used, including for example, an action like a two-finger spreading in motion to celebrate the introduction in secondary visualizations, where the axis defined by two point of contact determines that showed advanced secondary visualizations highlighted and / or expanded. In various embodiments, a hierarchy of visualizations can be strengthened, and the user can navigate between the two or more levels of interactive visualizations same way.

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Process for the production of ultrapure galacto-oligosaccharides

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The Ritter Pharmaceuticals, Inc. patent solves the following problem:

Our analysis of this patent is as follows:

Ritter Pharmaceuticals, Inc.’s patent US 9200303 B2 deals with Process for the production of ultrapure galacto-oligosaccharides.
The present invention describes a process for preparing pure (95%) galacto-oligosaccharides (gos), starting from the forced low purities by the use of continuous microbiological preparations involving Saccharomyces cerevisiae and streptococcus thermophilics.

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