Substituted pyridine spleen tyrosine kinase (SYK) inhibitors

You’ve invested time, talent, and energy into making a dent in the universe with your invention and ideas. Now it’s time for Utility, Provisional or Design Patent Creation with PowerPatent software and services.

The Merck Sharp & Dohme Corp., , Merck Canada Inc. patent solves the following problem:

Spleen Tyrosine Kinase (SYK) is a protein tyrosine kinase described as a key mediator of immunoreceptor signaling a host of inflammatory cells including mast cells, B-cells, macrophages and neutrophils. These immunoreceptors, including Fc receptor and the B-cell receptor, is important for allergic diseases, and antibody-mediated autoimmune diseases and thus pharmacologically interfering SYK conceivably treat these diseases.

Our analysis of this patent is as follows:

Merck Sharp & Dohme Corp., , Merck Canada Inc.’s patent US 9376418 B2 deals with Substituted pyridine spleen tyrosine kinase (SYK) inhibitors.
invention provides certain substituted Pyridines of Formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, P3, R4, rcy, CY, and t as described here. invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated spleen tyrosine kinase (SYK) kinase.

The revolutionary TRAN&ASSOCIATES provides patent creation and management tools to help inventors protect their inventions using the patent system. Full lawyer support to complete and file the application is available.

Aerodynamic drag reducing apparatus

You’ve invested time, talent, and energy into making a dent in the universe with your invention and ideas. Now it’s time for Utility, Provisional or Design Patent Creation with PowerPatent software and services.

The Stemco Lp patent solves the following problem:

It is known that a significant amount of aerodynamic drag created when a car traveling at velocities typical in a modern way. This is due, in large part, to areas of low pressure prompting the back of the car. The lower the pressure becomes more pronounced as airflow over the vehicle separates from the surfaces vehicles. The event airflow separation also well known in aircraft wing design and, in this case, cause the wing stop.

Our analysis of this patent is as follows:

Stemco Lp’s patent US 9346496 B2 deals with Aerodynamic drag reducing apparatus.
A flight drag reducing apparatus for use in vehicles with lower surfaces that are not streamlined. facilities include folding panels that extend rearward for use in a drag reducing configuration and crushed for use in a space saving configuration.

The revolutionary TRAN&ASSOCIATES provides patent creation and management tools to help inventors protect their inventions using the patent system. Full lawyer support to complete and file the application is available.

Nutritional compositions with lipid globules with a core comprising vegetable lipids and a coating comprising phospholipids or polar lipids

Use PowerPatent’s Online Patent Filing Service to get quick patent protection for your great idea.

The N.V. Nutricia patent solves the following problem:

Breast-feeding is the preferred method of infant feeding. However, there are circumstances that make breast-feeding impossible or less attractive. In the case of children's formula is a good alternative. The composition of modern infant formulas is adapted in such a way that will meet many of the special nutritional needs of the fast growing and developing infant.

Our analysis of this patent is as follows:

N.V. Nutricia’s patent US 9320294 B2 deals with Nutritional compositions with lipid globules with a core comprising vegetable lipids and a coating comprising phospholipids or polar lipids.
The present invention relates to a nutritional composition for children and / or children consisting of a lipid component that has a large volume lipid globule. composition can be used to prevent obesity and / or improve body composition later in life. Said lipid component comprises 10-50 wt% vegetable lipid, and the lipid globules with a number-laden diameter up to 1.0 m and / or a diameter of 2-12 m in an amount of at least 45 vol%.

The revolutionary TRAN&ASSOCIATES provides patent creation and management tools to help inventors protect their inventions using the patent system. Full lawyer support to complete and file the application is available.

Information environment map

Use PowerPatent’s Online Patent Filing Service to get quick patent protection for your great idea.

The Domo, Inc. patent solves the following problem:

Our analysis of this patent is as follows:

Domo, Inc.’s patent US 9299170 B1 deals with Information environment map.
Information presented on a map like a map of the city, with the relevant information to different groups of neighborhoods. Such a display method takes advantage of spatial cognition to provide an organizational and presentational devices that users can more easily remember where to look and find the right information. Metadata, notifications, and / or other auxiliary information may be presented with or cast on the data itself.

The revolutionary TRAN&ASSOCIATES provides patent creation and management tools to help inventors protect their inventions using the patent system. Full lawyer support to complete and file the application is available.

Trailer sail

Be the First-to-File and Protect your earth-moving ideas with PowerPatent software service for Online Patent Application

The Vanguard National Trailer Corporation patent solves the following problem:

Fairings used to improve the aerodynamics of a vehicle and are often added to the outside of a car to reduce drag while in motion. Fairings can be added to many places in the tractor and trailers to promote the launch of these great vehicles. In the past, the fairings included front and rear of the tractor as before, on, under, and behind the trailers. Fairings also placed in front of and behind the wheels of a trailer to improve aerodynamics.

Our analysis of this patent is as follows:

Vanguard National Trailer Corporation’s patent US 9296433 B2 deals with Trailer sail.
A flexible trailer fairing for reducing aerodynamic drag in a trailer on the road revealed. A fourfold flexible fairing system can be used to reduce the drag from the trailer's landing gear and wheel assembly. Many systems in keeping with the flexible fairing teaching while continuing to use also disclosed.

The revolutionary TRAN&ASSOCIATES provides patent creation and management tools to help inventors protect their inventions using the patent system. Full lawyer support to complete and file the application is available.

Method for initiating a consumable-based cycle of operation

Use PowerPatent’s Online Patent Filing Service to get quick patent protection for your great idea.

The Whirlpool Corportion patent solves the following problem:

The invention relates to the use of consumables through a communication device on a network creatures, and especially, the choice of appliance from a plurality of appliances that have an event associated with consumable.

Our analysis of this patent is as follows:

Whirlpool Corportion’s patent US 9277188 B2 deals with Method for initiating a consumable-based cycle of operation.
One way to start a cycle of operation based on a consumable includes providing a consumable reader with a software architecture configured to image data, talk on the one network, and recognition functionalities of appliances based on a unique identification associated with each time a functionality, imaging data of the consumable use consumable reader; Taking cycle data associated with the consumable based on imaged data; know, the software architecture in at least one activity associated with the data cycle; selecting from the plurality of appliances is an appliance with at least one activity using the unique identifier associated with a time of at least one event; and communicating the data cycle to the selected appliance on the network the appliances where the selected appliance becomes a cycle of operation associated with the consumable usage data cycle.

The revolutionary TRAN&ASSOCIATES provides patent creation and management tools to help inventors protect their inventions using the patent system. Full lawyer support to complete and file the application is available.

Compositions having reduced frictional coefficient, method of manufacture thereof and articles comprising the same

Patent Registration – Protect your earth-moving ideas with PowerPatent software service for Online Patent Application

The Sabic Global Technologies B.V. patent solves the following problem:

It disclosure relates to compositions that reduce frictional coefficients, means to do so, and articles comprising the same.

Our analysis of this patent is as follows:

Sabic Global Technologies B.V.’s patent US 9169371 B2 deals with Compositions having reduced frictional coefficient, method of manufacture thereof and articles comprising the same.
Expressed here is a composition consisting of an organic polymer and about 2 to 10 weight percent of an ionic liquid. The ionic liquid can be a halogenated or non-halogenated ionic liquid. Also disclosed in articles made from the composition.

The revolutionary TRAN&ASSOCIATES provides patent creation and management tools to help inventors protect their inventions using the patent system. Full lawyer support to complete and file the application is available.

Bipyridylaminopyridines as Syk inhibitors

You’ve invested time, talent, and energy into making a dent in the universe with your invention and ideas. Now it’s time to make sure it’s protected with a PowerPatent Utility, Provisional or Design Patent Application

The Merck Sharp & Dohme Corp., , Merck Canada Inc. patent solves the following problem:

Spleen Tyrosine Kinase (SYK) is a protein tyrosine kinase described as a key mediator of immunoreceptor signaling a host of inflammatory cells including mast cells, B-cells, macrophages and neutrophils. These immunoreceptors, including Fc receptor and the B-cell receptor, is important for allergic diseases, and antibody-mediated autoimmune diseases and thus pharmacologically interfering SYK conceivably treat these diseases.

Our analysis of this patent is as follows:

Merck Sharp & Dohme Corp., , Merck Canada Inc.’s patent US 9145391 B2 deals with Bipyridylaminopyridines as Syk inhibitors.
The present invention provides new pyrimidine amines of formula I are potent inhibitor of spleen tyrosine kinase, or prodrugs thereof, and useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD and rheumatoid arthritis and cancer.

The revolutionary TRAN&ASSOCIATES provides patent creation and management tools to help inventors protect their inventions using the patent system. Full lawyer support to complete and file the application is available.

Antibodies which bind to signal peptide-containing molecules

Protect your idea by filing a Provisional or Utility Patent Application with the PowerPatent Patent Service. It’s easy and fully backed by patent lawyers – and you don’t have to pay until you’re done.

The Incyte Corporation patent solves the following problem:

Protein transport is essential for cellular function. Transport in a protein may be mediated by a peptide signal located at the amino terminal protein itself. The signal peptide consists of ten to twenty hydrophobic amino acids that target the nascent protein from ribosome to a particular membrane bound compartment such as the endoplasmic reticulum (ER). Protein target the ER to continue by way secretory or stay in any of the secretory organelles such as the ER, Golgi apparatus, or lysosomes. Proteins that transit through the secretory way be secreted into the extracellular space or left in the plasma membrane. Secreted proteins are often synthesized as inactive precursors because of the post-translation processing events during transit through the secretory way. Such events include glycosylation, phosphorylation, proteolysis, and removal of the signal peptide with a signal peptidase. The other events that occur during the transport proteins include chaperone-dependent expression and folding of nascent proteins and protein interaction with a receptor or pore complex. Examples of secreted proteins with amino terminal signal peptide described below and include the receptor, extracellular matrix molecules, cytokines, hormones, growth and diversity factor, neuropeptides, vasomediators, phosphokinases, phosphatases, phospholipases, phosphodiesterases, G and Ras-related protein, Ion channels, pedagogue / pump, proteases, and transcription factors. (Reviewed in Alberts, B. et al. (1994) Molecular Biology of the Cell, garland Publishing, New York, NY, pp. 557-560, 582-592.)

Our analysis of this patent is as follows:

Incyte Corporation’s patent US 9102745 B2 deals with Antibodies which bind to signal peptide-containing molecules.
human invention provides signal peptide-containing proteins (HSPP) and polynucleotides which identify and encode HSPP. invention also provides expression vector, host cells, antibodies, agonists and antagonists. invention also provides methods for diagnosing, treating, or preventing diseases associated with expression of HSPP.

The revolutionary TRAN&ASSOCIATES provides patent creation and management tools to help inventors protect their inventions using the patent system. Full lawyer support to complete and file the application is available.

System and method for kernel rootkit protection in a hypervisor environment

Patent Registration – Protect your earth-moving ideas with PowerPatent software service for Online Patent Application

The Mcafee, Inc. patent solves the following problem:

In the field of computer network security has become more important and complicated in today's society. about Computer network configured for virtually every business or organization, often with many interconnected computer (for example, the end user computers, laptops, servers, printing devices, etc.). Moreover, the cloud service providers (and other organizations that run multiple applications and operating systems) may use hypervisor technology to run on various different guest operating systems simultaneously on a host device. A hypervisor is a computer software / hardware platform virtualization software that allows multiple operating systems to run on a host computer simultaneously. security threat may come from outside and internally in hypervisor environment. These threats to the hypervisor environment present further challenges for IT administrators.

Our analysis of this patent is as follows:

Mcafee, Inc.’s patent US 9069586 B2 deals with System and method for kernel rootkit protection in a hypervisor environment.
A system and method for protection rootkit in a hypervisor environment includes modules for creating a soft whitelist entries corresponding to each visitor flesh page to a guest operating system in a hypervisor environment, where each entry is a copy of the page to the corresponding page guest flesh, creating a page fault when a process tries to access a page visitor flesh, and teach the process corresponding page article. If the page fault is a data page faults, the method includes hard page faults, and marking a page table entry corresponding to the guest kernel pages as non-executable and writeable. If the page is wrong is a wrong instruction page, the method involves marking a page table entry corresponding to the page flesh guest as read-only. Redirecting changing a page frame number in a shadow page table hypervisor to teach the corresponding duplicate pages.

The revolutionary TRAN&ASSOCIATES provides patent creation and management tools to help inventors protect their inventions using the patent system. Full lawyer support to complete and file the application is available.