Substituted pyridine spleen tyrosine kinase (SYK) inhibitors

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The Merck Sharp & Dohme Corp., , Merck Canada Inc. patent solves the following problem:

Spleen Tyrosine Kinase (SYK) is a protein tyrosine kinase described as a key mediator of immunoreceptor signaling a host of inflammatory cells including mast cells, B-cells, macrophages and neutrophils. These immunoreceptors, including Fc receptor and the B-cell receptor, is important for allergic diseases, and antibody-mediated autoimmune diseases and thus pharmacologically interfering SYK conceivably treat these diseases.

Our analysis of this patent is as follows:

Merck Sharp & Dohme Corp., , Merck Canada Inc.’s patent US 9376418 B2 deals with Substituted pyridine spleen tyrosine kinase (SYK) inhibitors.
invention provides certain substituted Pyridines of Formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, P3, R4, rcy, CY, and t as described here. invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated spleen tyrosine kinase (SYK) kinase.

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Dynamic expansion of data visualizations

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The Domo, Inc. patent solves the following problem:

Our analysis of this patent is as follows:

Domo, Inc.’s patent US 9202297 B1 deals with Dynamic expansion of data visualizations.
A user can dynamically present and control the performance of secondary visualizations of data based on a selected element in a main data-aw. Introduction of secondary data visualizations presented as the user interact with the first look. In response to user input, the introduction can be dynamically expanded, allowing a user to dynamically drill down to select the elements in the first data-aw. Any input mechanisms should be used, including for example, an action like a two-finger spreading in motion to celebrate the introduction in secondary visualizations, where the axis defined by two point of contact determines that showed advanced secondary visualizations highlighted and / or expanded. In various embodiments, a hierarchy of visualizations can be strengthened, and the user can navigate between the two or more levels of interactive visualizations same way.

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Method for treating cancer using an antibody that inhibits notch4 signaling

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The The Regents Of The University Of Michigan patent solves the following problem:

Cancer remains the number two cause of death in this country, resulting in more than 500,000 deaths each year. Despite progress in detection and treatment, cancer mortality remains high. Despite remarkable progress in understanding the molecular basis of cancer, this knowledge has not yet translated into effective therapeutic strategies.

Our analysis of this patent is as follows:

The Regents Of The University Of Michigan’s patent US 9089556 B2 deals with Method for treating cancer using an antibody that inhibits notch4 signaling.
invention provides methods for treating cancer by administering to a patient having a solid tumor in a therapeutically effective amount of an antibody against Delta-like ligand 4 (Dll4) or others notch road components. The strong tumor may contain strong tumor stem cells.

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Extended graphics context with common compositing

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The Z124 patent solves the following problem:

This relates generally to the field of mobile environments Computing, and especially to support many user environment through the use of multiple operating systems on a single mobile computing device.

Our analysis of this patent is as follows:

Z124’s patent US 9077731 B2 deals with Extended graphics context with common compositing.
Cross-around providing support and companionship user to provide a seamless computing experience in a multi-operating system environment Computing. The multi-operating system computing environments may include a mobile operating system and a desktop operating system running simultaneously and independently on a mobile device Computing. The mobile operating system may be associated with a first user environment and desktop operating systems may be associated with a second user environment. Real-time display of the applications running on the mobile operating system in the second user environment provided by the translation application with a high graphics context of mobile operating systems. Using graphic for many applications translated into about a graphics frame. The mobile computing device may be a smartphone running the Android mobile operating system and a complete desktop Linux distribution on a modified Android kernel.

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Instant remote rendering

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The Z124 patent solves the following problem:

This application relates generally to the field around the mobile computing, and especially to support many user environment through the use of multiple operating systems on a single mobile computing device.

Our analysis of this patent is as follows:

Z124’s patent US 9047102 B2 deals with Instant remote rendering.
Cross-around providing support and companionship user to provide a seamless computing experience in a multi-operating system environment Computing. The multi-operating system computing environments may include a mobile operating system and a desktop operating system running simultaneously and independently on a mobile device Computing. Real-time or instant display of an application running on the mobile operating system in an environment of desktop operating systems which provide graphic applications for the application in the desktop operating system. A console application in desktop operating systems can access the information face for applications from shared memory and renders the application in a console window Computing environment associated with the desktop operating system. The mobile computing device may be a smartphone running the Android mobile operating system and a complete desktop Linux distribution on a modified Android kernel.

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User interaction across cross-environment applications through an extended graphics context

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The Z124 patent solves the following problem:

This application relates generally to the field around the mobile computing, and especially to support many user environment through the use of multiple operating systems on a single mobile computing device.

Our analysis of this patent is as follows:

Z124’s patent US 8933949 B2 deals with User interaction across cross-environment applications through an extended graphics context.
Cross-around providing support and companionship user to provide a seamless computing experience in a multi-operating system environment Computing. The multi-operating system computing environments may include a mobile operating system and a desktop operating system running simultaneously and independently on a shared grain on a mobile device Computing. User interaction management support includes input events initially shared grain received by receiving input events in desktop operating systems and translation, mapping, and / or through the event input through a virtual input device to mobile operating system as the application of mobile operating systems to receive the input events as if coming from a user interaction in the mobile operating system. The mobile computing device may be a smartphone running the Android mobile operating system and a complete desktop Linux distribution on a modified Android kernel.

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Lid for closing a cup

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The Constantia Teich Gmbh patent solves the following problem:

Our analysis of this patent is as follows:

Constantia Teich Gmbh’s patent US 8905251 B2 deals with Lid for closing a cup.
A lid (2) for the end of a cup (1) by a peripheral sealing edge (10) and a method for the production of such a lid. lid includes at least one aluminum film and an optionally multi-layered plastic layer that is co-extruded film to aluminum and has a closed predetermined tear lines (3). The plastic layer made of plastic based on polyethylene (PE) or plastic based on polypropylene (PP), and the predetermined tearing line introduced into the plastic layer preferably with a CO2 laser. The predetermined tear lines (3) can be given directly to the sealing edge region (10).

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Immune stimulatory infant nutrition

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The N. V. Nutricia patent solves the following problem:

Breastfeeding optimally supports the development of children and protects against infection. However, not all infants are in a position to receive human milk. It is therefore a continuing aim to provide infant formula, which simulates the functions of human milk. In addition to the desired compositional similarity between the formula and human milk, it is also particularly desirable to mimic the protective effects of human milk. Human milk for example been shown that human milk protects against infections and allergies.

Our analysis of this patent is as follows:

N. V. Nutricia’s patent US 8580316 B2 deals with Immune stimulatory infant nutrition.
A nutritional or pharmaceutical composition comprising fat, protein, carbohydrate, whey and casein given. composition has a weight ratio of casein to whey between 1: 1 to 1: 2.4 and comprises: a) at least 3 grams arginine per 100 grams protein; b) at least 10 wt. % Linoleic acid based on total fatty acids; c) at least 1 wt. % Alpha linolenic acid based on total fatty acids; d) at least one long-chain polyunsaturated fatty acid in an amount exceeding 0.1 wt. % Based on total fatty acid selected from docosahexaenoic acid, arachidonic acid and eicosapentaenoic acid; e) 5 to 25 wt. % At least one polyunsaturated fatty acid based on total fatty acids; and 2 to 12 grams indigestible oligosaccharides with a degree of polymerisation of 2 to 100 per 100 program dry weight of the composition. Methods of treatment by administering the compositions also given.

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Method for simulating the functional attributes of human milk oligosaccharides in formula-fed infants

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The Mead Johnson Nutrition Company patent solves the following problem:

(1) Field of Invention

Our analysis of this patent is as follows:

Mead Johnson Nutrition Company’s patent US 7572474 B2 deals with Method for simulating the functional attributes of human milk oligosaccharides in formula-fed infants.
The present invention is directed to a novel method for increasing the production of acetate, reduced production of butyrate, increasing the population and species of beneficial bacteria and slowing the rate of fermentation of prebiotics within the gut a formula-fed children. method comprising administration of a therapeutically effective amount of PDX in children.

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Method and system for home medical management

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The Stephanie Ward patent solves the following problem:

The present invention relates to a computer-based system and method for managing medical and personal information emergency one.

Our analysis of this patent is as follows:

Stephanie Ward’s patent US 7260586 B1 deals with Method and system for home medical management.
The present invention relates to a method and system for home medical supervision in a report, a one-page, one-sided, printed records seen by the naked eye in the medical and personal emergency information generated. The report was adapted to be used on a daily basis and brought the man. A first template provided to enter data relating to emergency contact information, medical history information and personal information. The second template is given to enter the second data with information related to medicine. The first and second data on the map in predetermined areas in the report. The report is generated that includes emergency contact information with a section on emergency contacts, medical history information in a medical history section, the personal information in a personal information section and the treatment information in a section of the medical information. The first pattern may also provide for the entry of data and information related to insurance and pharmacy information and other forms of information. The treatment section of the report may include rows representing every kind of medication by name. The section of the treatment may also include columns referring to a graphic illustration of each medication, the dosage, the doctor prescribing the information and the time of day for taking each medication. The report can be used as a life saving device in an emergency situation to provide emergency personnel with the necessary information. The report also can be used during the visits to the doctor and hospital stays to eliminate mistakes and in a daily basis to handle getting the individual drugs.

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