Nutrition with non-viable Bifidobacterium and non-digestible oligosaccharide

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The N.V. Nutricia patent solves the following problem:

A human child is fed human milk develop after birth in an intestinal microbiota rich in lactic acid bacteria. This is due to the presence of non-digestible saccharides on human milk specifically fermented with lactic acid bacteria, particularly bifidobacteria.

Our analysis of this patent is as follows:

N.V. Nutricia’s patent US 9456629 B2 deals with Nutrition with non-viable Bifidobacterium and non-digestible oligosaccharide.
A child and / or child nutrition containing non-viable Bifidobacterium breve and a non-digestible oligosaccharide and its use revealed.

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Compounds

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The Glaxo Group Limited patent solves the following problem:

Syk is a non-receptor tyrosine kinase involved in coupling activated immunoreceptors signal consuming events that mediate diverse cellular responses, including proliferation, distinction, and phagocytosis. Syk is widely expressed in hematopoietic cells. Syk inhibitor with potential anti-inflammatory and immunomodulating activities. They inhibit SYK-mediated IgG Fc epsilon and gamma receptor and BCR receptor signaling, resulting in inhibition of activation of mast cells, macrophages, and B-cells and relevant inflammatory responses and tissue damage. Mast cells play a major role in type I hypersensitivity reactions associated with urticaria, bronchial asthma, anaphylaxis and other allergic conditions. Therefore, SYK inhibitor has attracted interest from a number of therapeutic areas, including the treatment of rheumatoid arthritis, B-cell lymphoma, asthma, rhinitis and cutaneous disorders such as acute and chronic urticaria, mastocytosis, cutaneous lupus , atopic dermatitis, autoimmune bullous conditions including Pemphigus and pemphigoid and other mast cell mediated skin disease.

Our analysis of this patent is as follows:

Glaxo Group Limited’s patent US 9447074 B2 deals with Compounds.
A compound of formula (I): or a salt thereof; which is an inhibitor of spleen tyrosine kinase (SYK) and therefore potential use in the treatment of diseases resulting from inappropriate activation of mast cells, macrophages, and B-cells and related inflammatory responses and tissue damage, for example inflammatory diseases and / or allergic conditions, in cancer therapy, especially heme malignancies, and autoimmune conditions.

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Adjustable side under-ride guard for sliding axle trailer

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The Stephen Allen Batzer, , Patrick Keith Rogers patent solves the following problem:

The recognized hazard of side collision against dragged trailers traced at least back in 1938 that Robinson invented a peripheral guard for a hook-mounted trailer. See US Pat. No. 2,002,832. In his patent teaches a fixed whole periphery kept for a towed trailer with fixed rear axle. This non-regulated system to guard against the impact on the trailer from all directions.

Our analysis of this patent is as follows:

Stephen Allen Batzer, , Patrick Keith Rogers’s patent US 9352714 B2 deals with Adjustable side under-ride guard for sliding axle trailer.
A side under-ride collision guard described configured sitting in a large trailer equipped with a sliding rear axle, consisting of one or more energy absorbing structures cut wood axially adjustable for the position included in a multiplicity of similar barriers to diminish the impact hazard to other users paths presented lower axial edge (s) in the cargo compartment of the region (s) among the back the wheels of the trailer and the trailer back under-ride guard and / or between a stationary side under-ride guard and publicly trailer's wheels.

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Halogen-free, fireproof, transparent thermoplastic compositions having high thermomechanical strength, in particular for encapsulation in photovoltaic modules

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The Arkema France patent solves the following problem:

Our analysis of this patent is as follows:

Arkema France’s patent US 9331215 B2 deals with Halogen-free, fireproof, transparent thermoplastic compositions having high thermomechanical strength, in particular for encapsulation in photovoltaic modules.
A transparent, fireproof thermoplastic composition which is free from halogen compounds and include a polyamide-block graft copolymer formed a polyolefin backbone and, on average, at least one polyamide graft. The grafts attached to the backbone by the radicals of an unsaturated monomer (X) has a function able to react in a polyamide, and the radicals of the unsaturated monomer (X) is attached to the roots the backbone by grafting or co-polymerisation of the double bond. composition includes, as a weight percentage of the total composition: 90 to 99 wt% of polyamide-block graft copolymer, and 1 to 10 wt% of metal salts of phosphoric acid.

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Composition for flexible membranes

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The Sika Technology Ag patent solves the following problem:

Our analysis of this patent is as follows:

Sika Technology Ag’s patent US 9309400 B2 deals with Composition for flexible membranes.
A composition including a styrene block copolymer, a polar-modified styrene block copolymer, plant fibers and a polyolefin strong at 25 C., and the molten body, especially the membranes, made from such compositions.

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Pyrazolyl derivatives as Syk inhibitors

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The Merck Sharp & Dohme Corp., , Merck Canada Inc. patent solves the following problem:

Spleen Tyrosine Kinase (SYK) is a protein tyrosine kinase described as a key mediator of immunoreceptor signaling a host of inflammatory cells including mast cells, B-cells, macrophages and neutrophils. These immunoreceptors, including Fc receptor and the B-cell receptor, is important for allergic diseases, and antibody-mediated autoimmune diseases and thus pharmacologically interfering SYK conceivably treat these diseases.

Our analysis of this patent is as follows:

Merck Sharp & Dohme Corp., , Merck Canada Inc.’s patent US 9242984 B2 deals with Pyrazolyl derivatives as Syk inhibitors.
The present invention provides new pyrazole derivatives of formula I are potent inhibitor of spleen tyrosine kinase, and is useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD, rheumatoid arthritis, and cancer .

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Dynamic expansion of data visualizations

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The Domo, Inc. patent solves the following problem:

Our analysis of this patent is as follows:

Domo, Inc.’s patent US 9202297 B1 deals with Dynamic expansion of data visualizations.
A user can dynamically present and control the performance of secondary visualizations of data based on a selected element in a main data-aw. Introduction of secondary data visualizations presented as the user interact with the first look. In response to user input, the introduction can be dynamically expanded, allowing a user to dynamically drill down to select the elements in the first data-aw. Any input mechanisms should be used, including for example, an action like a two-finger spreading in motion to celebrate the introduction in secondary visualizations, where the axis defined by two point of contact determines that showed advanced secondary visualizations highlighted and / or expanded. In various embodiments, a hierarchy of visualizations can be strengthened, and the user can navigate between the two or more levels of interactive visualizations same way.

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Policy update apparatus, policy management system, policy update method, policy management method and recording medium

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The Nec Corporation patent solves the following problem:

Technology manager at a software policy that making the information into one resource is known.

Our analysis of this patent is as follows:

Nec Corporation’s patent US 9183009 B2 deals with Policy update apparatus, policy management system, policy update method, policy management method and recording medium.
The present invention provides a policy update tool to update a policy right software configuration changes equivalent to a resource. The update policy tools including policy acquisition means receives a sign resource, read an installation destination resource sign corresponding to the sign of the resources from the resource management means that by providing a mapping between signs that resources and resource-installed destinations characterizing an installation destination resource resource resource recognized the signs installed, and read the policy software corresponding to the signs and resources to install destination resource identification, and policy updates means that software update policy, gather and compare the updated software resource policy signs and install the sign destination resources, and food storage policy through.

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Cross-environment communication framework

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The Z124 patent solves the following problem:

This relates generally to the field of mobile environments Computing, and especially to support many user environment through the use of multiple operating systems on a single mobile computing device.

Our analysis of this patent is as follows:

Z124’s patent US 9098437 B2 deals with Cross-environment communication framework.
A mobile computing devices with a mobile operating systems and desktop operating systems running simultaneously and independently on a shared grain without virtualization. The mobile operating system provides a user experience for mobile computing devices that case the mobile environment. The desktop operating system provides a complete desktop user experience when the mobile computing device is docked to a secondary terminal around. Applications in desktop operating systems to communicate with applications and services in the mobile operating system with a framework cross-communication environment. The cross-premises communication structure may include interfaces to the remotable object to allow the process of mobile operating systems and processes in desktop operating systems to share the memory of a thread-safe manner. The mobile computing device may be a smartphone running the Android mobile operating system and a complete desktop Linux distribution on a modified Android kernel.

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Method for treating cancer using an antibody that inhibits notch4 signaling

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The The Regents Of The University Of Michigan patent solves the following problem:

Cancer remains the number two cause of death in this country, resulting in more than 500,000 deaths each year. Despite progress in detection and treatment, cancer mortality remains high. Despite remarkable progress in understanding the molecular basis of cancer, this knowledge has not yet translated into effective therapeutic strategies.

Our analysis of this patent is as follows:

The Regents Of The University Of Michigan’s patent US 9089556 B2 deals with Method for treating cancer using an antibody that inhibits notch4 signaling.
invention provides methods for treating cancer by administering to a patient having a solid tumor in a therapeutically effective amount of an antibody against Delta-like ligand 4 (Dll4) or others notch road components. The strong tumor may contain strong tumor stem cells.

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