Pea protein peptides with anti Helicobacter pylori activity

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The N.V. Nutricia patent solves the following problem:

Abdominal infections are a major problem for many people, and especially children and patients with an impaired immune system or abdominal pain. The result of the disease can be fatal. Stomach infection often caused by Escherichia coli, Salmonella, Campylobacter, Porphyromonas gingivalis, Clostridium, Enterobacter and Helicobacter, such as Helicobacter pylori.

Our analysis of this patent is as follows:

N.V. Nutricia’s patent US 8999924 B2 deals with Pea protein peptides with anti Helicobacter pylori activity.
The invention relates to a composition comprising pea protein hydrolyzate for the treatment and / or prevention of infection in the stomach pathogens, in particular Helicobacter pylori and / or a disease associated with infection of the stomach pathogen in said mammal.

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Billing modifier module for integrated emergency medical transportation database system

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The Golden Hour Data Systems, Inc. patent solves the following problem:

This invention relates to an integrated system of medical database. More specifically, this invention relates to a billing modifier module for a medical database of emergency medical transportation industry.

Our analysis of this patent is as follows:

Golden Hour Data Systems, Inc.’s patent US 8788378 B2 deals with Billing modifier module for integrated emergency medical transportation database system.
An integrated medical database system for business emergency medical transportation. The system includes a dispatch and demographic module, a clinical module, an administration module and a billing module. Each module to communicate data with one or more other modules to form a system for use in data sharing, thus achieving an end-to-end automation emergency care in medical accounting. Internal consistency checks made by the system to ensure that proper treatments made according to a choice diagnosis. The system includes a billing modifier module operate at data from dispatch and demographic module. In one embodiment, the billing module used modifier Geographic Practice Cost Index (GPCI) and Metropolitan Statistical Area (MSA) modifiers billing based on change computerized signature to give a more accurate word for the payer. The results of the billing module modifier sent to the billing module.

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Secreted proteins

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The Incyte Corporation patent solves the following problem:

Protein transport and secretion is necessary for cellular function. Transport protein mediated a signal peptide located at amino terminal protein dad or hidden. The signal peptide consists of ten to twenty hydrophobic amino acids that target the nascent protein from ribosome to a particular membrane bound compartment such as the endoplasmic reticulum (ER). Protein target the ER to continue by way secretory or stay in any of the secretory organelles such as the ER, Golgi apparatus, or lysosomes. Proteins that transit through the secretory way be secreted into the extracellular space or left in the plasma membrane. Protein retained in the plasma membrane includes one or more transmembrane domains, each consisting of 20 hydrophobic amino acid residues. Secreted protein normally synthesized as inactive precursors because of the post-translation processing events during transit through the secretory way. Such events include glycosylation, proteolysis, and removal of the signal peptide with a signal peptidase. The other events that occur during the transport proteins include chaperone-dependent expression and folding of nascent proteins and protein interaction with a receptor or pore complex. Examples of secreted proteins with amino terminal signal peptide described below and include protein with an important role in cell-to-cell signaling. Such proteins include transmembrane receptor and cell surface markers, extracellular matrix molecules, cytokines, hormones, growth and diversity factor, enzyme, neuropeptides, vasomediators, cell surface markers, and antigen recognition molecules. (Reviewed in Alberts, B. et al. (1994) Molecular Biology of the Cell, garland Publishing, New York, NY, pp. 557-560, 582-592.)

Our analysis of this patent is as follows:

Incyte Corporation’s patent US 8569445 B2 deals with Secreted proteins.
human invention provides secreted protein (SECP) and polynucleotides which identify and encode SECP. invention also provides expression vector, host cells, antibodies, agonists and antagonists. invention also provides methods for diagnosing, treating, or preventing diseases associated with aberrant expression of SECP.

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Aerodynamic fittings for trailer crossmembers

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The Steven Todd Kron patent solves the following problem:

The things that influence fuel economy of semi-trucks, aerodynamics is the field that the greatest progress will be made soon. Two types of flying drag, friction drag and pressure drag, pressure drag has a particularly significant impact on heavy trucks, accounting for as much as 90% of the drag force. In a standard, unmodified truck and trailer, approximately a third of this pressure drag causes the vehicle undercarriage.

Our analysis of this patent is as follows:

Steven Todd Kron’s patent US 8550541 B1 deals with Aerodynamic fittings for trailer crossmembers.
The purpose of the device is to reduce the fuel consumption of heavy trucks by improving airflow along the underside of a trailer, using a series of rectangular panel to close the gap between trailer crossmembers and performance a continuous smooth surface. These panels are placed between adjacent crossmembers and strengthened their flanges with a large clamping mechanism. Each clamp consists of a U nut fitted to the edge of the panel and a half clip is locked down. With U nut clamping on the topside of the flange and half clip gripping the lower face of the crossmember, these clamps secure each panel in place. These fittings, requiring no changes to the crossmembers themselves, easily installed and easily removable.

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Nutrition with lipids and non-digestible saccharides

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The N. V. Nutricia patent solves the following problem:

The gut barrier lines in the gastro-intestinal tract and separates the luminal, outside of the body from the systemic, internal organ. It protects the body from entering the luminal enemies, such as antigens, toxins and pathogens. The gut barrier consists of intestinal epithelium, a continuous monolayer pillars of epithelial cells, enterocytes, bound by protein complexes, such as tight junctions. A tenuous gut barrier function in children, where the gut before maturated enough. Also malnourished people, the patients fasted for surgery and intensive care patients the gut barrier disrupted.

Our analysis of this patent is as follows:

N. V. Nutricia’s patent US 8241659 B2 deals with Nutrition with lipids and non-digestible saccharides.
The invention relates to a liquid nutrition containing short chain fatty acyl chains and a non-digestible, give a saccharide. composition is particularly suitable for use as a child nutrition. composition is suitable for the treatment and / or prevention of gut barrier related diseases.

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Nutrition containing fat blend

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The N.V. Nutricia patent solves the following problem:

The polyunsaturated fatty acid status of infants is of continuing interest in art. Some functions dedicated to different fatty acids. For example, docosahexaenoic acid (DHA) is the primary structural fatty acid component in both the gray matter of the brain and the retina of the eye and thus is essential for brain and eye function. Therefore, DHA of particular importance for the growing child.

Our analysis of this patent is as follows:

N.V. Nutricia’s patent US 8053471 B2 deals with Nutrition containing fat blend.
The invention relates to the use of long chain polyunsaturated fatty acids for the manufacture of a nutritional composition for feeding infants of a mother who suffered from a metabolic disorder during pregnancy and a corresponding composition. Said composition comprising a n-3 polyunsaturated fatty acid fraction containing at least 0.1 wt docosahexaenoic acid (DHA) based on total weight of the lipid, at least 0.01 wt% n-3 docosapentaenoic acid ( Dpan-3) based on total weight of the lipid, and at least 0.01 wt. % Eicosapentaenoic acid (EPA) based on total weight of the lipid, where the amount of DHA, Dpan-3 EPA and less than 1 wt. % Total lipid.

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Crystalline anhydrate with anticholinergic efficacy

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The Boehringer Ingelhein International Gmbh patent solves the following problem:

Tiotropium bromide is known from European Patent Application EP 418 716 A1 and the following chemical structure:

Our analysis of this patent is as follows:

Boehringer Ingelhein International Gmbh’s patent US 7968717 B2 deals with Crystalline anhydrate with anticholinergic efficacy.
The invention relates to a new crystalline anhydrate of tiotropium bromide, the process of preparing it and use it for the preparation of a pharmaceutical composition for the treatment of respiratory complaints, especially for treatment COPD (chronic obstructive pulmonary disease) and asthma.

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Crystalline forms of tiotropium bromide

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The Boehringer Ingelheim International Gmbh patent solves the following problem:

Tiotropium bromide is known from European Patent Application EP 418 716 A1 and the following chemical structure:

Our analysis of this patent is as follows:

Boehringer Ingelheim International Gmbh’s patent US 7879871 B2 deals with Crystalline forms of tiotropium bromide.
The invention relates to a new crystalline form of tiotropium bromide, processes for preparing them and their use in preparing a pharmaceutical composition for the treatment of respiratory complaints, especially for the treatment of COPD (chronic obstructive pulmonary disease) and asthma.

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Integrated emergency medical transportion database and virtual private network system

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The Golden Hour Data Systems, Inc. patent solves the following problem:

This invention relates to an integrated system of medical database. More specifically, this invention relates to providing a safe communication and user permission for a medical database of emergency medical transportation industry.

Our analysis of this patent is as follows:

Golden Hour Data Systems, Inc.’s patent US 7668736 B2 deals with Integrated emergency medical transportion database and virtual private network system.
A system and method for providing secure communication of data and user access authority for an integrated emergency medical transportation database. The secure communication and user authority given through a Virtual Private Network (VPN), allowing confidential patient medical records to be transmitted through a public network like the Internet without compromising the confidentiality of the data.

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BTL-II proteins

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The Immunex Corporation patent solves the following problem:

Modulation of an immune or inflammatory response can be a valuable tool to control various types of diseases including autoimmune diseases, diseases characterized by abnormal inflammation and / or immune response, and infections . In treating diseases characterized by abnormal inflammation and / or immune responses, such as inflammatory bowel disease and autoimmune or inflammatory diseases, modulation of an immune response is desirable. In other situations, for example when the vaccine to a patient to give immunity to an infectious disease, stimulation of an immune response is desirable. In the case of vaccines, adjuvants on an immune response to a coadministered antigen can be valuable in providing long term protection against the disease. Particularly lacking in the art is the adjuvants capable of stimulating a mucosal immune response. A mucosal immune response, as opposed to a systemic immune response, is valuable because it attacks an infection with a very common point of entry, that is, to a mucosal surface. The present invention addresses these needs in the art by providing therapeutic agents for the diagnosis and treatment of diseases characterized by inadequate and / or abnormal inflammation and / or immune response and therapeutic agents that act as adjuvants to stimulate an immune response, particularly a mucosal immune response.

Our analysis of this patent is as follows:

Immunex Corporation’s patent US 7244822 B2 deals with BTL-II proteins.
invention provides isolated BTL-II protein, nucleic acid, antibody, enemies, and agonists and methods of making and using the same. Diagnostic, screening, and therapeutic methods of using the compositions of the invention given. For example, the composition of the invention can be used for diagnosis and treatment of inflammatory intestinal diseases and for the development of a mucosal immune response to an antigen.

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