Nasal administration

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The Optinose As patent solves the following problem:

Our analysis of this patent is as follows:

Optinose As’s patent US 8875704 B2 deals with Nasal administration.
A delivery device and method to deliver a powdered substance, in particular a triptan, such as sumatriptan, the anal region of a nasal cavity of a subject, in particular for the treatment of headache head, for example, cluster headaches and migraine, and neuropathic pain, the delivery device comprising: a nosepiece for insertion into a nasal cavity of a subject with which the powdered substance delivered to the posterior region of the nasal cavity of the subject, in particular on the bottom two thirds of the nasal cavity; and a substance supply unit that is operable to deliver the powdered substance through the nosepiece.

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Consumable holder with process control apparatus

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The Whirlpool Corporation patent solves the following problem:

The invention relates to devices that hold consumables used or operated by a communication tool.

Our analysis of this patent is as follows:

Whirlpool Corporation’s patent US 8461959 B2 deals with Consumable holder with process control apparatus.
A consumable holder with a source of a consumable, a first appliance coupling point configured to receive a resource of expression or consumable resources in an appliance configured to use consumable and resources in a physical operation on an article, a process control tool to prevent car or consumable resources in and out of the consumable holder, and a second appliance coupling point communication with process control equipment and configured to connect to an instrument. Thus, an appliance with consumable holder communicate with the process control equipment by the second set point.

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Apparatus for reducing drag on a vehicle

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The Lonnie Litchfield patent solves the following problem:

The present invention relates to a drag reduction device attachable to a rear portion of a vehicle to reduce drag on the car. Furthermore, the present invention is directed to a method of producing and implementing drag reduction devices.

Our analysis of this patent is as follows:

Lonnie Litchfield’s patent US 8414064 B2 deals with Apparatus for reducing drag on a vehicle.
The present invention is directed to a device for reducing the drag of a car. The device consists of a sheet of material and a plurality of depressions / elevations. The sheet material having a base portion and an apex extending from the base portion.

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Impact-resistant composition based on a polyamide resin and on a blend of at least one graft copolymer with polyamide blocks and a low-density ethylene polymer

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The Arkema France patent solves the following problem:

The improvement in impact strength of polyamides are usually obtained by integrating, in the form of a dispersed phase, an impact modifier which is elastomeric in nature and have reactive functional groups (acrylic acid, maleic anhydride, etc.) can react with the functional groups, such as NH2 chain end, the polyamide matrix. reactivity This makes it possible to ensure a fine homogeneous dispersion of the elastomer by controlling the size of the particles or nodules, a good adhesion to the nodule / matrix interface, and obtain a highest increase in impact strength. However, the drawback of this approach is the thickening of the blend, because the modifier coupling PA-effects, which leads to a significant fall in the melt flow. This great change in viscosity disrupt the processing of the composition, especially for thin or large-sized injection-molded parts, and extrusion.

Our analysis of this patent is as follows:

Arkema France’s patent US 8410216 B2 deals with Impact-resistant composition based on a polyamide resin and on a blend of at least one graft copolymer with polyamide blocks and a low-density ethylene polymer.
The invention relates to a composition based on an impact-resistant thermoplastic polyamide resin, which contains, as a blendfrom 60 to 98 wt% of polyamide resin (A) andfrom 2 to 40 wt% of a combination of at least one graft copolymer with polyamide blocks (B) comprising a polyolefin backbone and at least one polyamide graft in which the grafts attached to the backbone by the residues of an unsaturated monomer (X) having a functional group able to react in a wet-terminated polyamide, the residues of the unsaturated monomer (X) attached to the backbone by grafting or copolymerization via its double bond, and a non -sumbalik ethylenic polymer (C) is miscible in (B) and has a density below 0.960 g / cm3.

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Heat stable nutritional beverage and method of preparing it

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The Campina Nederland Holding B.V. patent solves the following problem:

A heat strong, whey-containing nutritional drink known from WO 2006/119064, which describes a novel aseptic drink and pudding that contains at least 2% whey, and a process for making it.

Our analysis of this patent is as follows:

Campina Nederland Holding B.V.’s patent US 8263164 B2 deals with Heat stable nutritional beverage and method of preparing it.
A heat strong nutritional drink with a pH of 6.6-8.2 containing 5-12% w / w whey protein obtained through the use of 4-16% w / w at least one sugar chosen from non-oligo- and polysaccharides, wherein at least one monosaccharide other than glucose.

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Nutrition with lipids and non-digestible saccharides

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The N. V. Nutricia patent solves the following problem:

The gut barrier lines in the gastro-intestinal tract and separates the luminal, outside of the body from the systemic, internal organ. It protects the body from entering the luminal enemies, such as antigens, toxins and pathogens. The gut barrier consists of intestinal epithelium, a continuous monolayer pillars of epithelial cells, enterocytes, bound by protein complexes, such as tight junctions. A tenuous gut barrier function in children, where the gut before maturated enough. Also malnourished people, the patients fasted for surgery and intensive care patients the gut barrier disrupted.

Our analysis of this patent is as follows:

N. V. Nutricia’s patent US 8241659 B2 deals with Nutrition with lipids and non-digestible saccharides.
The invention relates to a liquid nutrition containing short chain fatty acyl chains and a non-digestible, give a saccharide. composition is particularly suitable for use as a child nutrition. composition is suitable for the treatment and / or prevention of gut barrier related diseases.

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Polynucleotides encoding signal peptide-containing molecules

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The Incyte Corporation patent solves the following problem:

Protein transport is essential for cellular function. Transport in a protein may be mediated by a peptide signal located at the amino terminal protein itself. The signal peptide consists of ten to twenty hydrophobic amino acids that target the nascent protein from ribosome to a particular membrane bound compartment such as the endoplasmic reticulum (ER). Protein target the ER to continue by way secretory or stay in any of the secretory organelles such as the ER, Golgi apparatus, or lysosomes. Proteins that transit through the secretory way be secreted into the extracellular space or left in the plasma membrane. Secreted proteins are often synthesized as inactive precursors because of the post-translation processing events during transit through the secretory way. Such events include glycosylation, phosphorylation, proteolysis, and removal of the signal peptide with a signal peptidase. The other events that occur during the transport proteins include chaperone-dependent expression and folding of nascent proteins and protein interaction with a receptor or pore complex. Examples of secreted proteins with amino terminal signal peptide described below and include the receptor, extracellular matrix molecules, cytokines, hormones, growth and diversity factor, neuropeptides, vasomediators, phosphokinases, phosphatases, phospholipases, phosphodiesterases, G and Ras-related protein, Ion channels, pedagogue / pump, proteases, and transcription factors. (Reviewed in Alberts, B. et al. (1994) Molecular Biology of the Cell, garland Publishing, New York, NY, pp. 557-560, 582-592.)

Our analysis of this patent is as follows:

Incyte Corporation’s patent US 8153398 B2 deals with Polynucleotides encoding signal peptide-containing molecules.
human invention provides signal peptide-containing proteins (HSPP) and polynucleotides which identify and encode HSPP. invention also provides expression vector, host cells, antibodies, agonists and antagonists. invention also provides methods for diagnosing, treating, or preventing diseases associated with expression of HSPP.

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Nutrition containing fat blend

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The N.V. Nutricia patent solves the following problem:

The polyunsaturated fatty acid status of infants is of continuing interest in art. Some functions dedicated to different fatty acids. For example, docosahexaenoic acid (DHA) is the primary structural fatty acid component in both the gray matter of the brain and the retina of the eye and thus is essential for brain and eye function. Therefore, DHA of particular importance for the growing child.

Our analysis of this patent is as follows:

N.V. Nutricia’s patent US 8053471 B2 deals with Nutrition containing fat blend.
The invention relates to the use of long chain polyunsaturated fatty acids for the manufacture of a nutritional composition for feeding infants of a mother who suffered from a metabolic disorder during pregnancy and a corresponding composition. Said composition comprising a n-3 polyunsaturated fatty acid fraction containing at least 0.1 wt docosahexaenoic acid (DHA) based on total weight of the lipid, at least 0.01 wt% n-3 docosapentaenoic acid ( Dpan-3) based on total weight of the lipid, and at least 0.01 wt. % Eicosapentaenoic acid (EPA) based on total weight of the lipid, where the amount of DHA, Dpan-3 EPA and less than 1 wt. % Total lipid.

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Method for simulating the functional attributes of human milk oligosaccharides

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The Mead Johnson Nutrition Company patent solves the following problem:

(1) Field of Invention

Our analysis of this patent is as follows:

Mead Johnson Nutrition Company’s patent US 8021708 B2 deals with Method for simulating the functional attributes of human milk oligosaccharides.
The present invention is directed to a novel method for increasing the production of acetate, reduced production of butyrate, increasing the population and species of beneficial bacteria and slowing the rate of fermentation of prebiotics within the gut a formula-fed children. method comprising administration of a therapeutically effective amount of PDX in children.

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Pyrazolo[3,4-b]pyridine compounds, and their use as PDE4 inhibitors

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The Glaxo Group Limited patent solves the following problem:

Phosphodiesterase 4 inhibitor (PDE4 inhibitor) may be useful in treating and / or Branch Tomato in a variety of diseases / conditions, especially inflammatory and / or allergic diseases, in mammals such as humans, for example -ingnan: chronic obstructive pulmonary disease (COPD) (eg chronic bronchitis and / or emphysema), asthma, rhinitis (eg allergic or non-allergic rhinitis), rheumatoid arthritis, atopic dermatitis, psoriasis, urticaria, allergic conjunctivitis, vernal conjunctivitis, eosinophilic granuloma, septic shock, inflammatory bowel disease (eg ulcerative colitis and / or Crohn's disease), reperfusion injury of the myocardium and / or brain, chronic glomerulonephritis, endotoxic shock, or adult respiratory distress syndrome, in mammals such as humans .

Our analysis of this patent is as follows:

Glaxo Group Limited’s patent US 8003663 B2 deals with Pyrazolo[3,4-b]pyridine compounds, and their use as PDE4 inhibitors.
invention provides N – {[1,6-diethyl-4- (tetrahydro-2H-pyran-4-ylamino) -1H-pyrazolo [3,4-b] pyridin-5-YL] methyl} -4 – ({8 – [ (2-hydroxyethyl) (methyl) amino] octanoyl} amino) benzamide, whose formula is or a salt thereof, as the monohydrochloride salt thereof. the invention also provides the use of the compound or salt as inhibitor of phosphodiesterase type IV (PDE4) and / or for the treatment and / or Branch Tomato inflammatory and / or allergic diseases such as chronic obstructive pulmonary disease (COPD), asthma , or rhinitis (eg allergic and / or non-allergic rhinitis).

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