Compounds

Protect your invention by filing a Provisional or Utility Patent Application using our software today! It’s easy and fully backed by patent lawyers – and you don’t have to pay until you’re done.

The Glaxo Group Limited patent solves the following problem:

Syk is a non-receptor tyrosine kinase involved in coupling activated immunoreceptors signal consuming events that mediate diverse cellular responses, including proliferation, distinction, and phagocytosis. Syk is widely expressed in hematopoietic cells. Syk inhibitor with potential anti-inflammatory and immunomodulating activities. They inhibit SYK-mediated IgG Fc epsilon and gamma receptor and BCR receptor signaling, resulting in inhibition of activation of mast cells, macrophages, and B-cells and relevant inflammatory responses and tissue damage. Mast cells play a major role in type I hypersensitivity reactions associated with urticaria, bronchial asthma, anaphylaxis and other allergic conditions. Therefore, SYK inhibitor has attracted interest from a number of therapeutic areas, including the treatment of rheumatoid arthritis, B-cell lymphoma, asthma, rhinitis and cutaneous disorders such as acute and chronic urticaria, mastocytosis, cutaneous lupus , atopic dermatitis, autoimmune bullous conditions including Pemphigus and pemphigoid and other mast cell mediated skin disease.

Our analysis of this patent is as follows:

Glaxo Group Limited’s patent US 9447074 B2 deals with Compounds.
A compound of formula (I): or a salt thereof; which is an inhibitor of spleen tyrosine kinase (SYK) and therefore potential use in the treatment of diseases resulting from inappropriate activation of mast cells, macrophages, and B-cells and related inflammatory responses and tissue damage, for example inflammatory diseases and / or allergic conditions, in cancer therapy, especially heme malignancies, and autoimmune conditions.

The revolutionary TRAN&ASSOCIATES provides patent creation and management tools to help inventors protect their inventions using the patent system. Full lawyer support to complete and file the application is available.

BTK inhibitors

Be the First-to-File and Protect your earth-moving ideas with PowerPatent software service for Online Patent Application

The Merck Sharp & Dohme Corp. patent solves the following problem:

B lymphocyte activation is key to the generation of adaptive immune responses. Derailed B lymphocyte activation is a sign of many autoimmune diseases and in the modulation of the immune response and therapeutic interest. Recently the success of B cell therapy in autoimmune disease is established. Treatment of rheumatoid arthritis (RA) patients with Rituximab (anti-CD20 therapy) is an accepted clinical therapy today. More recent clinical trial studies showed that treatment with Rituximab also ameliorates symptoms of the disease in relapsing remitting multiple sclerosis (RRMS) and systemic lupus erythematosus (murder) patients. This success supports the potential for future therapies for autoimmune diseases targeted B cell immunity.

Our analysis of this patent is as follows:

Merck Sharp & Dohme Corp.’s patent US 9446130 B2 deals with BTK inhibitors.
The present invention provides Bruton's tyrosine kinase (Btk) inhibitor compounds according to Formula I or pharmaceutically acceptable salt thereof. Formula I or a pharmaceutically acceptable salt thereof or pharmaceutical compositions comprising these compounds and their use in therapy. In particular, the present invention relates to the use of Btk inhibitor compounds for the treatment of Btk mediated disorder.

The revolutionary TRAN&ASSOCIATES provides patent creation and management tools to help inventors protect their inventions using the patent system. Full lawyer support to complete and file the application is available.

Adjustable side under-ride guard for sliding axle trailer

File for Quick & Easy Patent Protection with PowerPatent.

The Stephen Allen Batzer, , Patrick Keith Rogers patent solves the following problem:

The recognized hazard of side collision against dragged trailers traced at least back in 1938 that Robinson invented a peripheral guard for a hook-mounted trailer. See US Pat. No. 2,002,832. In his patent teaches a fixed whole periphery kept for a towed trailer with fixed rear axle. This non-regulated system to guard against the impact on the trailer from all directions.

Our analysis of this patent is as follows:

Stephen Allen Batzer, , Patrick Keith Rogers’s patent US 9352714 B2 deals with Adjustable side under-ride guard for sliding axle trailer.
A side under-ride collision guard described configured sitting in a large trailer equipped with a sliding rear axle, consisting of one or more energy absorbing structures cut wood axially adjustable for the position included in a multiplicity of similar barriers to diminish the impact hazard to other users paths presented lower axial edge (s) in the cargo compartment of the region (s) among the back the wheels of the trailer and the trailer back under-ride guard and / or between a stationary side under-ride guard and publicly trailer's wheels.

The revolutionary TRAN&ASSOCIATES provides patent creation and management tools to help inventors protect their inventions using the patent system. Full lawyer support to complete and file the application is available.

Automated suggested alerts based on natural language and user profile analysis

Protect your idea by filing a Provisional or Utility Patent Application with the PowerPatent Patent Service. It’s easy and fully backed by patent lawyers – and you don’t have to pay until you’re done.

The Domo, Inc. patent solves the following problem:

Our analysis of this patent is as follows:

Domo, Inc.’s patent US 9235978 B1 deals with Automated suggested alerts based on natural language and user profile analysis.
An alert suggestion generator to automatically suggest alert for a user based on user input. The user input may include natural language text and / or user actions that suggestion generator able to generate alert that there is a high tendency to relate, and therefore will, to the user. Each alert will have a reason for existence as the passage of time, the measure of a numeric metric, or other factors. Each alert also has a state proclamation clear how the user is announced. The alert suggestion generator to get a user profile of the user in addition to determining how alert that is most relevant to the user. The user will be queried to confirm the alert, and the alert that they set. Partial alarm will be generated and user can be queried for the trigger condition and / or state announcement needed to complete the alert.

The revolutionary TRAN&ASSOCIATES provides patent creation and management tools to help inventors protect their inventions using the patent system. Full lawyer support to complete and file the application is available.

Wear and friction properties of engineering thermoplastics with ultra-high molecular weight polyethylene

Patent Registration – Protect your earth-moving ideas with PowerPatent software service for Online Patent Application

The Sabic Global Technologies B.V. patent solves the following problem:

Ultra-high molecular weight polyethylene (UHMWPE) has a very high melt viscosity that makes conventional processing techniques such as screw extrusion and injection molding difficult to fulfill. Thus, the use of UHMWPE limited. Polyetherimide (PEI), and polyetheretherketone (Peek) is used in a variety of lubricated applications such as gears, bearings, and rollers, for example.

Our analysis of this patent is as follows:

Sabic Global Technologies B.V.’s patent US 9181430 B2 deals with Wear and friction properties of engineering thermoplastics with ultra-high molecular weight polyethylene.
Said here is the composition comprising a polymer comprising polyetherimide, polyetheretherketone, polyamide, polyoxyalkylene or polyalkylene terephthalate, or a mixture thereof, and ultra-high molecular weight polyethylene, where the ultra- high molecular weight polyethylene covers a surface modifier. Also disclosed are articles containing one or more of the species composition. abstract It is intended as a scanning tool for purposes of searching in the particular art and is not intended to limit the present invention.

The revolutionary TRAN&ASSOCIATES provides patent creation and management tools to help inventors protect their inventions using the patent system. Full lawyer support to complete and file the application is available.

Resonant leaky-mode photonic elements and methods for spectral and polarization control

Use PowerPatent’s Online Patent Filing Service to get quick patent protection for your great idea.

The University Of Connecticut patent solves the following problem:

The present disclosure relates to a strategic new areas of optical devices and, particularly, the Optical devices based on sound dripped through each modulated films.

Our analysis of this patent is as follows:

University Of Connecticut’s patent US 8718415 B2 deals with Resonant leaky-mode photonic elements and methods for spectral and polarization control.
Optical devices with versatile spectral values ​​given charged with one or more modulated and uniform layers to realize drip-mode resonance operation and a versatile spectral-band design. The first and / or higher number of evanescent diffraction orders applied to excite one or more dropped by. The one- or two-dimensional each building, carved by the proper distribution of the materials in each period, have a result that is or asymmetric profile allowing an expanded range sound devices drop-mode realized. Therefore, the quality of the optical permit devices, among other things, race alongside resonance frequency or wavelength, easily forming the reflection and transmission spectra for the optical device to be fulfilled, and the resonance wavelength areas that can be precisely controlled to affect the size of the drop can be with each other. Moreover, the corrupt profile allows for accurate spectral distance interactive dropped by to give greater flexibility to the Optical design device.

The revolutionary TRAN&ASSOCIATES provides patent creation and management tools to help inventors protect their inventions using the patent system. Full lawyer support to complete and file the application is available.

Drag reducing apparatus for a vehicle

Protect your invention by filing a Provisional or Utility Patent Application using our software today! It’s easy and fully backed by patent lawyers – and you don’t have to pay until you’re done.

The Aerodynamic Trailer Systems, Llc patent solves the following problem:

Various devices are known to increase the flight efficiency of a truck, semi trailer, or other large moving objects. It has long been recognized that the rectangular high profile figure in these cars and the speeds needed for the increase in travel flight drag. Reduce aerodynamic drag will significantly reduce the overall fuel consumption and harmful air emissions. The present disclosure relates to the increase in air inflatable life for back or face the aft face of a transport trailer, for example, the wind deflector boattails be mounted on trailers that use the swing or roll up door with a box van or other trailers that often operate at speeds routinely in excess of 35 mph.

Our analysis of this patent is as follows:

Aerodynamic Trailer Systems, Llc’s patent US 8444210 B2 deals with Drag reducing apparatus for a vehicle.
The present disclosure provides for drag reduction in a moving things through the atmosphere, thus increasing fuel efficiency. This is accomplished by tying an inflatable boattail (ie drag reducer) to the aft face or the back end of a vehicle or trailer, thus delaying the flow separation to a point further downstream and reduce the intensity of the negative pressure in the aft face.

The revolutionary TRAN&ASSOCIATES provides patent creation and management tools to help inventors protect their inventions using the patent system. Full lawyer support to complete and file the application is available.

Anhdyrous lactose agglomerates and the preparation thereof

You’ve invested time, talent, and energy into making a dent in the universe with your invention and ideas. Now it’s time to make sure it’s protected with PowerPatent’s Utility, Provisional or Design Patent Filing Software

The Campina Nederland Holding B.V. patent solves the following problem:

Lactose is widely used as a filler, filler, binder or diluent in tablets and capsules, and to a more limited extent on the lyophilized products, baby food formula, and as a carrier dry powder inhaler. Worldwide, whispered put the needs of their lactose monographs in the identity and purity of pharmaceutical grade lactose, thereby distinguishing between lactose monohydrate and anhydrous lactose. According to these medicines, anhydrous lactose must have a water content of at most 1 wt%, and for that reason particularly useful as excipient in moisture-sensitive applications.

Our analysis of this patent is as follows:

Campina Nederland Holding B.V.’s patent US 8173173 B2 deals with Anhdyrous lactose agglomerates and the preparation thereof.
The invention relates to a process for the preparation of anhydrous lactose agglomerates, said process comprising (i) subjecting essentially anhydrous lactose primary particles comprising at least 60 wt% lactose crystals in a granulator to a wet step granulation in a temperature range of 30-100 C. using a binder solution, which granulation mass subjected to dry for at least part of steps granulation, and (ii ) after dry granulation mass. The anhydrous lactose agglomerates comprising at least 50 wt% -lactose crystallites and a total water content in the range of 0-1.0 wt%, required by the standards laid down by the whispers anhydrous lactose excipients. These agglomerates combine with excellent compactibility and flowability properties and particularly useful as excipient in moisture-sensitive applications.

The revolutionary TRAN&ASSOCIATES provides patent creation and management tools to help inventors protect their inventions using the patent system. Full lawyer support to complete and file the application is available.

Packet mirroring between primary and secondary virtualized software images for improved system failover performance

You’ve invested time, talent, and energy into making a dent in the universe with your invention and ideas. Now it’s time to make sure it’s protected with a PowerPatent Utility, Provisional or Design Patent Application

The Avaya Inc. patent solves the following problem:

Repeated applications software using the state-of-the-art Virtual Machine (VM) technology platform and is a powerful and flexible way to provide high that guarantees the user application software. Using vendors can take advantage of VM technology to build confidence in their solution by making several photos (or copies) of the application software running synchronously, but independently of one another. These images can be run on the same physical device, for example, a general purpose application server, or in multiple, decoupled VM vessels, or they may develop across many physical computers decoupled vessels VM. Multiple VM replications plan is, but in general, VM solution to a leading image software that deliver software services for users and then to a secondary or tertiary backup image to a standby server that can up for the first in the event of a failure. The backup images generally synchronized at different intervals during the update of the data structures and database backup servers to track the changes that have occurred since the last time the update data simultaneously happened. called together and make these solutions provide dramatic improvements in the ability of a software application vendor to guarantee that users receive reliable access to services in software application.

Our analysis of this patent is as follows:

Avaya Inc.’s patent US 8145945 B2 deals with Packet mirroring between primary and secondary virtualized software images for improved system failover performance.
Packet loss on a standby server during failover results when the first fails. There is always a certain amount of packet traffic inbound to the first lost during the interval failover. With current solutions, this packet loss during the failover is inevitable. The problem is that when this information is lost, the standby is the case at the end of the work, so the standby state with information that is old and deputy state system only proper state system during the ever do. One solution is a way in which all inbound data package targets given to a leading software application, such as a virtualized software application, running on a virtual machine, continued monitor and copied to a copy Network Device for simultaneous delivery to a backup software application running on a standby system.

The revolutionary TRAN&ASSOCIATES provides patent creation and management tools to help inventors protect their inventions using the patent system. Full lawyer support to complete and file the application is available.

Guided-mode resonance sensors employing angular, spectral, modal, and polarization diversity for high-precision sensing in compact formats

Apply for Patent – Protect your earth-moving ideas with PowerPatent software service for Online Patent Application

The Robert Magnusson, , Wawro Debra D patent solves the following problem:

The present disclosure provides optical sensor that works with the sound of dripping through each structure which angular, spectral, modal, and polarization diversity beneficially applied for high-precision sensing systems in compact format. Cross-reference data set thus obtained, ready to numerical models, to provide an additional level of accuracy and precision to improve the quality of the sensing operation in a wide variety of applications.

Our analysis of this patent is as follows:

Robert Magnusson, , Wawro Debra D’s patent US 8111401 B2 deals with Guided-mode resonance sensors employing angular, spectral, modal, and polarization diversity for high-precision sensing in compact formats.
A guided mode resonance (GMR) sensor assembly and systems provided. The GMR sensor includes a waveguide structure configured for operation at or near one or more dropped by a receiver of input light from a light source to the waveguide structures to cause a or more dropped TE and TM sound manner and a detector for change in one or more parts, waveshape and / or magnitude of each of a TE resonance and a TM resonance by allowing them between the first and second physical states of said waveguide structure or the immediate environment.

The revolutionary TRAN&ASSOCIATES provides patent creation and management tools to help inventors protect their inventions using the patent system. Full lawyer support to complete and file the application is available.