Information environment map

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The Domo, Inc. patent solves the following problem:

Our analysis of this patent is as follows:

Domo, Inc.’s patent US 9299170 B1 deals with Information environment map.
Information presented on a map like a map of the city, with the relevant information to different groups of neighborhoods. Such a display method takes advantage of spatial cognition to provide an organizational and presentational devices that users can more easily remember where to look and find the right information. Metadata, notifications, and / or other auxiliary information may be presented with or cast on the data itself.

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Air fairing for frameless trailer

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The Mac Trailer Manufacturing, Inc. patent solves the following problem:

The present invention relates generally to systems and devices that increase aerodynamic efficiency. Particularly, the invention relates generally to a wind fairing or trailer skirts on trailers. In particular, the invention relates to an air fairing for a frameless trailer.

Our analysis of this patent is as follows:

Mac Trailer Manufacturing, Inc.’s patent US 9283998 B2 deals with Air fairing for frameless trailer.
An air fairing device connected to the bottom under a frameless trailer improve flight efficiency and improve fuel economy. A picture of the wind fairing device provides a wind deflector position ahead of a trolley that supports the frameless trailer on a back end. The second image in the air fairing device provides two things mounted under the frameless trailer. The first deflector is attached and handed down from one sustain arm, said arm connecting the trailer of a semi-tractor or truck. The second deflector connected below the bottom of the frameless trailer and positioned behind the first deflector and the side of the trolley. A third image is similar to the second, but further includes a third deflector positioned between the two axles of the trolley.

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Pyrazolyl derivatives as Syk inhibitors

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The Merck Sharp & Dohme Corp., , Merck Canada Inc. patent solves the following problem:

Spleen Tyrosine Kinase (SYK) is a protein tyrosine kinase described as a key mediator of immunoreceptor signaling a host of inflammatory cells including mast cells, B-cells, macrophages and neutrophils. These immunoreceptors, including Fc receptor and the B-cell receptor, is important for allergic diseases, and antibody-mediated autoimmune diseases and thus pharmacologically interfering SYK conceivably treat these diseases.

Our analysis of this patent is as follows:

Merck Sharp & Dohme Corp., , Merck Canada Inc.’s patent US 9242984 B2 deals with Pyrazolyl derivatives as Syk inhibitors.
The present invention provides new pyrazole derivatives of formula I are potent inhibitor of spleen tyrosine kinase, and is useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD, rheumatoid arthritis, and cancer .

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Automated suggested alerts based on natural language and user profile analysis

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The Domo, Inc. patent solves the following problem:

Our analysis of this patent is as follows:

Domo, Inc.’s patent US 9235978 B1 deals with Automated suggested alerts based on natural language and user profile analysis.
An alert suggestion generator to automatically suggest alert for a user based on user input. The user input may include natural language text and / or user actions that suggestion generator able to generate alert that there is a high tendency to relate, and therefore will, to the user. Each alert will have a reason for existence as the passage of time, the measure of a numeric metric, or other factors. Each alert also has a state proclamation clear how the user is announced. The alert suggestion generator to get a user profile of the user in addition to determining how alert that is most relevant to the user. The user will be queried to confirm the alert, and the alert that they set. Partial alarm will be generated and user can be queried for the trigger condition and / or state announcement needed to complete the alert.

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2-Pyridyl carboxamide-containing spleen tyrosine kinase (SYK) inhibitors

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The Merck Sharp & Dohme Corp. patent solves the following problem:

Spleen Tyrosine Kinase (SYK) is a protein tyrosine kinase described as a key mediator of immunoreceptor signaling a host of inflammatory cells including mast cells, B-cells, macrophages and neutrophils. These immunoreceptors, including Fc receptor and the B-cell receptor, is important for allergic diseases, and antibody-mediated autoimmune diseases and thus pharmacologically interfering SYK conceivably treat these diseases.

Our analysis of this patent is as follows:

Merck Sharp & Dohme Corp.’s patent US 9216173 B2 deals with 2-Pyridyl carboxamide-containing spleen tyrosine kinase (SYK) inhibitors.
invention provides certain 2-pyridyl formamide-containing compounds of Formula (I) or pharmaceutically acceptable salts thereof, wherein A and B as described here. invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated spleen tyrosine kinase (SYK) kinase.

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Bipyridylaminopyridines as Syk inhibitors

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The Merck Sharp & Dohme Corp., , Merck Canada Inc. patent solves the following problem:

Spleen Tyrosine Kinase (SYK) is a protein tyrosine kinase described as a key mediator of immunoreceptor signaling a host of inflammatory cells including mast cells, B-cells, macrophages and neutrophils. These immunoreceptors, including Fc receptor and the B-cell receptor, is important for allergic diseases, and antibody-mediated autoimmune diseases and thus pharmacologically interfering SYK conceivably treat these diseases.

Our analysis of this patent is as follows:

Merck Sharp & Dohme Corp., , Merck Canada Inc.’s patent US 9145391 B2 deals with Bipyridylaminopyridines as Syk inhibitors.
The present invention provides new pyrimidine amines of formula I are potent inhibitor of spleen tyrosine kinase, or prodrugs thereof, and useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD and rheumatoid arthritis and cancer.

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Drag reduction of a tractor trailer using guide vanes

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The Clarkson University patent solves the following problem:

The present invention relates to a vehicle with a gear mounted thereon for reducing aerodynamic drag and, particularly, to a guide vane device with an airfoil cross-section mounted on the aft part of a a tractor trailer.

Our analysis of this patent is as follows:

Clarkson University’s patent US 9139238 B2 deals with Drag reduction of a tractor trailer using guide vanes.
The present invention relates to a vehicle with a gear mounted thereon for reducing aerodynamic drag and, particularly, to a guide vane device with an airfoil cross-section mounted on the aft part of a a tractor trailer.

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Dual display cursive touch input

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The Z124 patent solves the following problem:

A substantial number of handheld devices Computing, such as cellular phones, tablets, and E-Readers, make use of a touch screen display will not only save the display information to the user, but also to take inputs from the user's command interface. While touch screen display can increase the configurability of the handheld device and to provide a wide variety of user interface options, this flexibility often comes at a price. The two use the touch screen to provide for and receive user commands, while flexible for the user, in order to obfuscate the display, and cause visual clutter, thus leading to user frustration and loss of yield.

Our analysis of this patent is as follows:

Z124’s patent US 9128659 B2 deals with Dual display cursive touch input.
These methods and devices including providing a device having at least a first screen and a secondary screen; receiving a first input, where the first input comprising a cursive input on the first screen; processing the first input to estimate a character based on previous input; to display the estimated character (s); and to exercise a choice, where the selection includes a choice of traits selected from the estimated character (s).

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Antibodies which bind to signal peptide-containing molecules

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The Incyte Corporation patent solves the following problem:

Protein transport is essential for cellular function. Transport in a protein may be mediated by a peptide signal located at the amino terminal protein itself. The signal peptide consists of ten to twenty hydrophobic amino acids that target the nascent protein from ribosome to a particular membrane bound compartment such as the endoplasmic reticulum (ER). Protein target the ER to continue by way secretory or stay in any of the secretory organelles such as the ER, Golgi apparatus, or lysosomes. Proteins that transit through the secretory way be secreted into the extracellular space or left in the plasma membrane. Secreted proteins are often synthesized as inactive precursors because of the post-translation processing events during transit through the secretory way. Such events include glycosylation, phosphorylation, proteolysis, and removal of the signal peptide with a signal peptidase. The other events that occur during the transport proteins include chaperone-dependent expression and folding of nascent proteins and protein interaction with a receptor or pore complex. Examples of secreted proteins with amino terminal signal peptide described below and include the receptor, extracellular matrix molecules, cytokines, hormones, growth and diversity factor, neuropeptides, vasomediators, phosphokinases, phosphatases, phospholipases, phosphodiesterases, G and Ras-related protein, Ion channels, pedagogue / pump, proteases, and transcription factors. (Reviewed in Alberts, B. et al. (1994) Molecular Biology of the Cell, garland Publishing, New York, NY, pp. 557-560, 582-592.)

Our analysis of this patent is as follows:

Incyte Corporation’s patent US 9102745 B2 deals with Antibodies which bind to signal peptide-containing molecules.
human invention provides signal peptide-containing proteins (HSPP) and polynucleotides which identify and encode HSPP. invention also provides expression vector, host cells, antibodies, agonists and antagonists. invention also provides methods for diagnosing, treating, or preventing diseases associated with expression of HSPP.

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Intestinal barrier integrity

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The N. V. Nutricia patent solves the following problem:

The stomach epithelium often acts as a barrier authority chose the absorption of nutrients, electrolytes and water and preventing the exposure to dietary and microbial antigens, including food allergens. The stomach epithelium limits the passage of antigens to the systemic circulation, which can cause inflammatory reactions, such as allergic reactions. As the incidence of allergies, especially food allergies is increasing, many research groups search for (preventive) cures for these diseases.

Our analysis of this patent is as follows:

N. V. Nutricia’s patent US 9084433 B2 deals with Intestinal barrier integrity.
the invention of a method for stimulating barrier integrity in a mammal by administering to a mammal a composition comprising: eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA) and arachidonic acid (ARA), and at least two different oligosaccharides.

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