Processes for making lactose utilizing pre-classification techniques and pharmaceutical formulations formed therefrom

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The Dmv-Fonterra Excipients Technology Gmbh, , Glaxo Group Limited patent solves the following problem:

In the field of inhalation therapy, it is generally desirable to use therapeutic molecules having a particle size (ie, diameter) in the range of 1 to 10 m. carrier molecule or excipients, such as lactose, canine therapeutic preparation also includes significantly larger diameter particles (for example, 100 to 150 m) which are not normally penetrate into the upper respiratory tract to the same degree as the active ingredient. In general, it is better to use a smaller particle size for the lactose or a lactose blend having a defined ratio of coarse and fine lactose.

Our analysis of this patent is as follows:

Dmv-Fonterra Excipients Technology Gmbh, , Glaxo Group Limited’s patent US 9365905 B2 deals with Processes for making lactose utilizing pre-classification techniques and pharmaceutical formulations formed therefrom.
A process for forming lactose suitable for use in a pharmaceutical formulation comprises providing a plurality of lactose particles containing no more than 10% w / w of lactose particles with a number average the particle size of about 70 microns or less; stands the plurality of lactose particles to yield a plurality of milled lactose particles with an average particle size, (D50), from 50 micron to 100 micron; and classifying the plurality of milled lactose particles at least two pieces consisting of a fine particle and a coarse particle in which the fine particle has an average particle size, (D50), from 3 microns to 50 microns, and the coarse particle has an average particle size, (D50), from 40 micron to 250 micron.

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Automatic web service monitoring

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The Domo, Inc. patent solves the following problem:

Our analysis of this patent is as follows:

Domo, Inc.’s patent US 9191285 B1 deals with Automatic web service monitoring.
According to various embodiments, the present invention provides a live site performance monitoring in the context of reasonable resource hierarchies found in cloud computing systems. In particular, in an image, the system of the present invention facilitates monitoring of new services Computing without necessarily requires clear knowledge of these new services. Such services may include, for example and without limitation, given the use of an image that State Transfer (REST) ​​architecture, although the techniques described herein may also be used in other architectures. In one embodiment, the system of the present invention works by automatically creating groups of things for performance monitoring, based on the hierarchy of a type. Heuristics can be used to determine aggregatable hierarchy nodes.

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Bipyridylaminopyridines as Syk inhibitors

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The Merck Sharp & Dohme Corp., , Merck Canada Inc. patent solves the following problem:

Spleen Tyrosine Kinase (SYK) is a protein tyrosine kinase described as a key mediator of immunoreceptor signaling a host of inflammatory cells including mast cells, B-cells, macrophages and neutrophils. These immunoreceptors, including Fc receptor and the B-cell receptor, is important for allergic diseases, and antibody-mediated autoimmune diseases and thus pharmacologically interfering SYK conceivably treat these diseases.

Our analysis of this patent is as follows:

Merck Sharp & Dohme Corp., , Merck Canada Inc.’s patent US 9145391 B2 deals with Bipyridylaminopyridines as Syk inhibitors.
The present invention provides new pyrimidine amines of formula I are potent inhibitor of spleen tyrosine kinase, or prodrugs thereof, and useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD and rheumatoid arthritis and cancer.

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Separation of screen usage for complex language input

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The Z124 patent solves the following problem:

A substantial number of handheld devices Computing, such as cellular phones, tablets, and E-Readers, make use of a touch screen display will not only save the display information to the user, but also to take inputs from the user's command interface. While touch screen display can increase the configurability of the handheld device and to provide a wide variety of user interface options, this flexibility often comes at a price. The two use the touch screen to provide for and receive user commands, while flexible for the user, in order to obfuscate the display, and cause visual clutter, thus leading to user frustration and loss of yield.

Our analysis of this patent is as follows:

Z124’s patent US 9104366 B2 deals with Separation of screen usage for complex language input.
These methods and devices including providing a device having at least a first screen and a secondary screen; receiving a first input, where the first input includes an input language on the first screen; processing the first input to estimate a character based on previous input; to display the estimated character (s); and to exercise a choice, where the selection includes a choice of traits selected from the estimated character (s).

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Cross-environment communication framework

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The Z124 patent solves the following problem:

This relates generally to the field of mobile environments Computing, and especially to support many user environment through the use of multiple operating systems on a single mobile computing device.

Our analysis of this patent is as follows:

Z124’s patent US 9098437 B2 deals with Cross-environment communication framework.
A mobile computing devices with a mobile operating systems and desktop operating systems running simultaneously and independently on a shared grain without virtualization. The mobile operating system provides a user experience for mobile computing devices that case the mobile environment. The desktop operating system provides a complete desktop user experience when the mobile computing device is docked to a secondary terminal around. Applications in desktop operating systems to communicate with applications and services in the mobile operating system with a framework cross-communication environment. The cross-premises communication structure may include interfaces to the remotable object to allow the process of mobile operating systems and processes in desktop operating systems to share the memory of a thread-safe manner. The mobile computing device may be a smartphone running the Android mobile operating system and a complete desktop Linux distribution on a modified Android kernel.

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Auto-waking of a suspended OS in a dockable system

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The Z124 patent solves the following problem:

This relates generally to the field of mobile environments Computing, and especially to support many user environment through the use of multiple operating systems on a single mobile computing device.

Our analysis of this patent is as follows:

Z124’s patent US 9026709 B2 deals with Auto-waking of a suspended OS in a dockable system.
A mobile computing devices with a mobile operating systems and desktop operating systems running simultaneously and independently on a shared grain without virtualization. The mobile operating system provides a user experience for mobile computing devices that case the mobile environment. The desktop operating system provides a complete desktop user experience when the mobile computing device is docked to a secondary terminal around. The desktop operating system will be suspended when the mobile computing device is not docked to a secondary terminal around and continued when the mobile computing device is docked to a secondary terminal environment that provides a desktop computing experience. The mobile computing device may be a smartphone running the Android mobile OS and a complete desktop Linux distribution on a modified Android kernel.

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Optical processing

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The Thomas Swan & Co. Ltd. patent solves the following problem:

It was proposed to use so-called spatial light modulators to control the routing of light beams in an optical system, for example from the choice of a number of input optical fibers of choice output fibers.

Our analysis of this patent is as follows:

Thomas Swan & Co. Ltd.’s patent US 8937759 B2 deals with Optical processing.
A modular routing node includes an input port and a number of output ports. The modular routing node arranged to generate a plurality of different brain and use small changes to compensate for the wavelength differences and alignment tolerances of an optical system. A Optical device arranged to receive a multiplex multiple optical signals with different wavelengths, to separate the optical signal into at least two groups, and the processing of at least one of the groups adaptively.

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Aligning segments of bar graphs for comparative analysis

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The Domo, Inc. patent solves the following problem:

Our analysis of this patent is as follows:

Domo, Inc.’s patent US 8914740 B1 deals with Aligning segments of bar graphs for comparative analysis.
A user interface for allowing a user to interact with a graphical display, to conduct a comparative look at the display elements. A bar graph or other quantitative display is provided, wherein each bar is divided into a plurality of parts. Responsive to user input, for a given species, in different bars, realigned one another along a common baseline, so that the area can be more easily compared to a a. At least one photo, the realignment passes, and the original graph restored upon further user input and / or after a predetermined period of time.

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Aerodynamic skirts for land vehicles

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The Eleanor Praskovskaya, , Andrew Praskovsky, , Alexander Praskovsky patent solves the following problem:

The invention relates to systems for reducing aerodynamic drag and mitigating adverse effects on the air side of the car to the ground and, especially, the flying skirts controlling the airflow under the car body by self flying adaptive way.

Our analysis of this patent is as follows:

Eleanor Praskovskaya, , Andrew Praskovsky, , Alexander Praskovsky’s patent US 8899660 B1 deals with Aerodynamic skirts for land vehicles.
the invention provides a navigational system and a method for controlling the airflow over a land vehicle by self-adaptive flight means alternatively essentially impenetrable barriers. The system comprises at least one flying skirt thrown under the car body. Each flight skirt is a society in airflow control elements that constitute a face edge. The elements could only a portion of the surface area and make the opening on the left side of the area. The airflow control elements configured to reduce vehicle air drag and mitigate harmful effects of side winds on the vehicle by generating optimum air streams on the door and out the door, performance rear air stream under the body and create flying lilo shield.

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Nasal administration

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The Optinose As patent solves the following problem:

Our analysis of this patent is as follows:

Optinose As’s patent US 8875704 B2 deals with Nasal administration.
A delivery device and method to deliver a powdered substance, in particular a triptan, such as sumatriptan, the anal region of a nasal cavity of a subject, in particular for the treatment of headache head, for example, cluster headaches and migraine, and neuropathic pain, the delivery device comprising: a nosepiece for insertion into a nasal cavity of a subject with which the powdered substance delivered to the posterior region of the nasal cavity of the subject, in particular on the bottom two thirds of the nasal cavity; and a substance supply unit that is operable to deliver the powdered substance through the nosepiece.

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